Publications by authors named "Qiu Yan Pei"

Objective: To investigate the clinical manifestations and laboratory indicators of anti-Sjögren's-syndrome-related antigen A (SSA) antibody associated fetal cardiac disease.

Methods: Pregnant women hospitalized at Peking University People's Hospital from January 2013 to July 2023 were included. Eleven patients with anti-SSA antibody positive were eventually diagnosed with fetal cardiac di-sease.

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Objectives: Establish a fetal heart anatomical cross-sectional database that correlates with screening transverse ultrasound images suggested by international professional organizations to detect congenital heart defects.

Methods: Fetuses with suspected congenital heart defects identified using the following cardiac image sequences obtained from transverse slices beginning from the upper abdomen and ending in the upper thorax were the subjects of this study: (1) four-chamber view, (2) left ventricular outflow tract view, (3) three-vessel right ventricular outflow tract view, and (4) the three-vessel tracheal view. A database of digital two-dimensional images of the transverse sweep was created for fetuses with confirmed congenital heart defects.

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Objective: To provide an anatomical basis for continuous transverse scanning of the fetal heart by analyzing the typical cross-sectional characteristics of different types of congenital heart deformities (CHDs) using an anatomical image database.

Materials And Methods: The database consisted of cross-sectional images obtained from 45 cases of common fetal CHDs, which were continuously displayed by the three-dimensional software Amira 5.3.

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Background: Fetal congenital heart anomalies are the most common congenital anomalies in live births. Fetal echocardiography (FECG) is the only prenatal diagnostic approach used to detect fetal congenital heart disease (CHD). FECG is not widely used, and the antenatal diagnosis rate of CHD varies considerably.

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Article Synopsis
  • The study aimed to create a database containing ultrathin cross-sectional images of fetal hearts affected by various congenital heart diseases (CHDs) for clinical use.
  • Forty fetal heart samples from induced labor were processed and photographed to generate detailed anatomical images, which were then imported into 3D software for further analysis.
  • The resulting database allows for dynamic visualization and study of fetal heart anatomy as well as aids in education for sonographers and students, with potential for expanding the library with more cases.
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Objective: We estimated the success rates of cytogenetic analyses in different tissue samples after intrauterine fetal deaths and analyzed the value of cytogenetic testing for determining the causes.

Methods: Women with intrauterine fetal deaths (occurring at > 10 weeks of gestation) were offered either invasive testing before medical induction of labor, or solid tissue biopsy diagnosis after delivery.

Results: A total cohort of 355 intrauterine fetal deaths was studied.

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