Biomineralized tetramethylpyrazine-loaded PCL/gelatin nanofibrous membrane promotes vascularization and bone regeneration of rat cranium defects.

Conventional electrospinning produces nanofibers with smooth surfaces that limit biomineralization ability. To overcome this disadvantage, we fabricated a tetramethylpyrazine (TMP)-loaded matrix-mimicking biomineralization in PCL/Gelatin composite electrospun membranes with bubble-shaped nanofibrous structures. PCL/Gelatin membranes (PG), PCL/Gelatin membranes containing biomineralized hydroxyapatite (HA) (PGH), and PCL/Gelatin membranes containing biomineralized HA and loaded TMP (PGHT) were tested.

[Clinical application of veno-arteriolization of finger lateral vein for repairing severed finger tips].

Objective: To investigate effect of veno-arteriolization of finger lateral vein for repairing severed finger tips.

Methods: From March 2007 to April 2012, 20 patients with severed finger tips were treated with veno-arteriolization of finger lateral vein after failure in anastomosing artery of finger over times. During operation, the dominant digital artery at proximal end and the dominant finger lateral vein at distal end was anastomosed as the blood supply, the non-superiorty finger lateral vein was anastomosed as the blood drainage.

[Repairing degloving injury of distal phalanx with homodigital bilobed flaps tiled].

Objective: To study the methods and effectiveness of repairing degloving injury of the distal phalanx with homodigital bilobed flaps tiled.

Methods: Between April 2008 and June 2011, 40 patients (40 fingers) with degloving injury of the distal phalanx were treated, which were caused by machine. There were 30 males and 10 females, aged from 18 to 56 years (mean, 30 years).