The synthesis of water-soluble and low-cytotoxicity quantum dots (QDs) in aqueous solution has received much attention recently. A one-step and convenient method has been developed for synthesis of water-soluble glutathione (GSH)-capped and Zn(2+)-doped CdTe QDs via a refluxing route. Because of the addition of Zn ions and the epitaxial growth of a CdS layer, the prepared QDs exhibit superior properties, including strong fluorescence, minimal cytotoxicity, and enhanced biocompatibility.
View Article and Find Full Text PDFToxicol In Vitro
October 2012
Quantum dots (QDs) have a great potential for applications in nanomedicine. However, a few studies showed that they also exhibited toxicity. We used Escherichia coli (E.
View Article and Find Full Text PDFJ Colloid Interface Sci
November 2011
Quantum dots (QDs) hold great potential for applications in nanomedicine, however, only a few studies investigate their toxic- and bio-effects. Using Escherichia coli (E. coli) cells as model, we found that CdTe QDs exhibited a dose-dependent inhibitory effect on cell growth by microcalorimetric technique and optical density (OD(600)).
View Article and Find Full Text PDFJ Colloid Interface Sci
March 2011
A simple method was developed for preparing CdSe quantum dots (QDs) using a common protein (bovine serum albumin (BSA)) to sequester QD precursors (Cd(2+)) in situ. Fluorescence (FL) and absorption spectra showed that the chelating time between BSA and Cd(2+), the molar ratio of BSA/Cd(2+), temperature, and pH are the crucial factors for the quality of QDs. The average QD particle size was estimated to be about 5 nm, determined by high-resolution transmission electron microscopy.
View Article and Find Full Text PDFWater-soluble, biological-compatible, and excellent fluorescent CdSe/CdS quantum dots (QDs) with L-cysteine as capping agent were synthesized in aqueous medium. Fluorescence (FL) spectra, absorption spectra, and transmission electron microscopy (TEM) were employed to investigate the quality of the products. The interactions between QDs and bovine serum albumin (BSA) were studied by absorption and FL titration experiments.
View Article and Find Full Text PDFColloids Surf B Biointerfaces
July 2010
The biological consequences of exposure to TiO2, UV light, and their combined effect were studied on the Escherichia coli (E. coli) cells. The damage of outer membrane was observed for the cells after treatment of TiO2 or UV light.
View Article and Find Full Text PDFPhotochem Photobiol
September 2010
The biological consequences of exposure to TiO(2), UV light and their combined effects were studied on the cellular envelopes of Tetrahymena. For Tetrahymena cells treated with TiO(2) or UV light alone, the cell membrane shrunk while still maintaining the original elliptoid shape. Cells treated by TiO(2) under UV light irradiation experienced the most serious damage by peroxidation.
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