Publications by authors named "Qishuai Guo"
Article Synopsis
- This study was a randomized controlled trial aimed at evaluating a new pilot hole preparation system for placing pedicle screws in minimally invasive lumbar fusion surgeries, comparing its efficacy and safety with traditional methods.
- A total of 60 patients were involved, and results showed that the new system significantly reduced the time needed for pilot hole preparation, screw placement, and fluoroscopy exposure compared to the conventional approach.
- Additionally, screw placement accuracy was better with the new system, indicating its potential for improved clinical outcomes in spinal surgeries.
Article Synopsis
- The study aimed to evaluate how age affects the prognosis of patients with pT1-2N1 breast cancer and its role in the decision to administer postmastectomy radiotherapy (PMRT).
- A total of 5,438 patients were analyzed using advanced statistical methods to correlate age with treatment outcomes over a median follow-up period of 67 months.
- Findings indicated that while younger patients (≤50 years) benefitted from PMRT in terms of reducing relapse and improving survival, older patients (>50 years) did not show the same benefits, revealing age as a crucial factor in treatment decisions.
Objective: To clarify the effect of postmastectomy radiotherapy (PMRT) on pTN breast cancer patients with different molecular subtypes.
Methods: We retrospectively analyzed the data of 5442 patients with pTN breast cancer treated using modified radical mastectomy in 11 hospitals in China. Univariate, multivariate, and propensity score matching (PSM) analyses were used to evaluate the effect of PMRT on locoregional recurrence (LRR).
The purpose of this study was to investigate the association of Epstein-Barr virus (EBV) with peripheral blood immune cell counts and clinical outcomes in advanced nasopharyngeal carcinoma (NPC) patients. In a retrospective design, 146 patients with NPC at stage IV were enrolled in this study. The association of EBV status with peripheral blood immune cell counts, distant metastases, and long-term survival in patients with advanced NPC were determined.
View Article and Find Full Text PDFBackground: The role of postmastectomy radiotherapy (PMRT) in women with pT1-T2N1 breast cancer is controversial. The authors developed a nomogram that was predictive for overall survival (OS) and identified patients who derived no benefit from PMRT.
Methods: The authors retrospectively evaluated 4869 patients with pT1-T2N1 breast cancer who were treated with mastectomy between 2000 and 2014 in 11 Chinese hospitals.
Introduction: To estimate the clinical impact of bolus in intensity-modulated radiotherapy (IMRT) and volumetric-modulated arc therapy (VMAT) for stage I-II nasal natural killer/T-cell lymphoma (NNKTCL), including target quality, organs at risk (OARs) sparing, and tumor control probability (TCP).
Methods: Two different treatment plans were designed in IMRT and VMAT for 10 stage I-II NNKTCL patients. The clinical plans added bolus perfectly contacting the nose skin, similar to common clinical planning design practices.
Purpose: The objective of this study is to estimate radiotherapy (RT) modalities for patients with stage I-II nasal natural killer T-Cell lymphoma (NNKTCL), including plan quality, radiation delivery efficiency, cost of RT and excess absolute risk (EAR).
Materials And Methods: Twenty-four representative patients with stage I-II NNKTCL treated with fix-field intensity-modulated radiotherapy (FF-IMRT) were re-planned for volumetric modulated arc therapy (VMAT), TomoDirect (TD) and TomoHelical (TH) on the TomoHDA system, respectively. Plan characteristics, cost of RT and EAR were compared.
Background: Antibodies have been proved to be effective in cancer treatment. Peroxiredoxin I (Prx I) is a potential target for cancer radiotherapy. The aim of this article is to investigate the effect of a novel phage display single-chain variable fragment (scFv) antibody targeting Prx I on human lung carcinoma cell line A549 radiosensitivity and the underlying mechanisms.
View Article and Find Full Text PDF[Effect of peroxiredoxin I gene silencing on the radiosensitivity of breast carcinoma MCF-7 cell xenograft in nude mice].
Nan Fang Yi Ke Da Xue Xue Bao
June 2011
Objective: To investigate the effect of peroxiredoxin I (Prx I) gene silencing on the radiosensitivity of breast carcinoma MCF-7 cell xenograft in nude mice and explore the mechanism.
Methods: MCF-7 cells were transfected with the recombinant plasmids pGPU6-PrxI and pGPU6-HK separately. The pGPU6-PrxI-transfected cells stably expressing Prx I shRNA and pGPU6-HK-transfected cells were inoculated subcutaneously into BALB/c nude mice.