Publications by authors named "Qisheng Fu"

Article Synopsis
  • PET waste is tough to break down and poses environmental issues, but upcycling it into valuable chemicals can help solve this problem and support a circular economy.
  • A study developed a multi-enzyme system in E. coli to convert terephthalic acid, derived from PET, into vanillin, achieving high production levels through metabolic engineering.
  • The engineered E. coli efficiently converted post-consumer PET waste into vanillin, demonstrating an eco-friendly method that also turns low-value waste into profitable products.
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Amylomaltases (AMs) play important roles in glycogen and maltose metabolism. However, the molecular mechanism is elusive. Here, we investigated the conformational dynamics of the 250s loop and catalytic mechanism of AM using path-metadynamics and QM/MM MD simulations.

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Gastric cancer is one of the leading prevalent and malignant cancers worldwide, especially in east Asia. However, the in-depth molecular mechanism underlying gastric cancer progression remains uncertain. Recently, studies have identified that long non-coding RNA (lncRNA) could play critical roles in the tumorigenesis of multiple types of cancer.

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