Publications by authors named "Qiqing Yang"
Article Synopsis
- - The study identifies alanyl-tRNA synthetases AARS1 and AARS2 as crucial sensors that detect L-lactate in cells and facilitate the process of lactylation on proteins, particularly affecting lysine residues.
- - AARS2 interacts with cGAS, resulting in its lactylation and subsequent inactivation, which hampers its ability to sense DNA and respond to immune challenges.
- - Blockade of MCT1 can restore cGAS function and enhance immune responses in stressed mice, suggesting a significant link between lactate metabolism and immune evasion mechanisms.
Article Synopsis
- Gut microbiota-derived metabolites play a crucial role in cancer development by altering the tumor environment and affecting important signaling pathways in cancer and immune cells.
- The integration of these metabolites into treatments like chemotherapy and immunotherapy enhances drug effectiveness and reduces side effects, while also addressing issues like drug resistance.
- Various techniques, including synthetic biology and fecal microbial transplantation, can modify microbial metabolites, but care must be taken due to context-dependent effects of these metabolites on cancer treatment outcomes.*
Calcium (Ca )/calmodulin (CaM)-dependent protein kinase (CCaMK) is an important positive regulator of antioxidant defenses and tolerance against oxidative stress. However, the underlying molecular mechanisms are largely unknown. Here, we report that the rice (Oryza sativa) CCaMK (OsDMI3) physically interacts with and phosphorylates OsUXS3, a cytosol-localized UDP-xylose synthase.
View Article and Find Full Text PDFArceuthobium (dwarf mistletoes) are hemiparasites that may cause great damage to infected trees belonging to Pinaceae and Cupressaceae. Currently, dwarf mistletoe control involves the use of the ethylene-producing product ethephon (ETH), which acts by inducing dwarf mistletoe shoot abscission. However, the process by which ETH functions is mostly unknown.
View Article and Find Full Text PDFA seroprevalence survey of Babesia gibsoni infection in dogs in East China was conducted using an ELISA with recombinant B. gibsoni thrombospondin-related adhesive protein (BgTRAP). A total of 1170 dogs from East China were examined and the seroprevalence was 9.
View Article and Find Full Text PDF[Investigation on wild resources of Dendrobium officinale distribution and ecological envirment in Anhui].
Zhongguo Zhong Yao Za Zhi
December 2013
The wild resources of Dendrobium officinale in Anhui province were studied by textural research, data collection, interview survey and regional survey, in order to investigate the resources distribution and ecological characters and provide the reference for Anhui Dendrobium industry. In this paper, a part of producing areas of wild D. officinale in Anhui province was selected to analyze the ecological characters.
View Article and Find Full Text PDFBackground: Monitoring traps and control methods are needed for the long-legged chafer, Hoplia spectabilis Medvedev, which has recently reached outbreak numbers in pastureland of Qinghai Province, China.
Results: Field trapping experiments, using cross-pane funnel (barrier) traps, showed that H. spectabilis adults were not significantly attracted to branches of the host plant Dasiphora fructicosa (L.