Publications by authors named "Qiongmin Zhang"

Article Synopsis
  • Alzheimer's disease (AD) diagnosis can be enhanced using a proposed lightweight network that combines multiple MRI views, addressing the limitations of both 2D and complex 3D analysis.
  • The network employs a multi-slice attention fusion module to maintain classification consistency and a personalized fusion module to weigh the importance of each MRI view.
  • Results indicate a substantial increase in accuracy and a reduction in computational resources, outperforming existing methods in distinguishing between AD, mild cognitive impairment (MCI), and healthy controls (CN).
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Alzheimer's disease (AD) is a progressive neurodegenerative disease. Early detection and intervention are crucial in preventing the progression of AD. To achieve efficient and scalable AD auto-detection based on structural Magnetic Resonance Imaging (sMRI), a lightweight neural network using multi-slice sMRI is proposed in this paper.

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Article Synopsis
  • Teicoplanin is an antibiotic that can potentially harm cochlear hair cells and has shown to cause cell death in tested cultures, prompting investigation into its effects.
  • The TIGAR protein plays a key role in promoting cell survival and its expression significantly decreases when cells are treated with teicoplanin, affecting cell viability and apoptosis levels.
  • Enhancing TIGAR expression can protect cells from teicoplanin-induced damage, and using antioxidants like N-acetyl-L-cysteine shows promise in reducing harmful effects, suggesting TIGAR could be a target for preventing ototoxicity.
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Alzheimer's disease (AD) is the most common form of dementia and there is no effective treatment currently. Using artificial intelligence technology to assist the diagnosis and intervention as early as possible is of great significance to delay the development of AD. Structural Magnetic Resonance Imaging (sMRI) has shown great practical values on computer-aided AD diagnosis.

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Magnetic resonance imaging (MRI) is by nature a multi-modality technique that provides complementary information about different aspects of diseases. So far no attempts have been reported to assess the potential of multi-modal MRI in discriminating individuals with and without migraine, so in this study, we proposed a classification approach to examine whether or not the integration of multiple MRI features could improve the classification performance between migraine patients without aura (MWoA) and healthy controls. Twenty-one MWoA patients and 28 healthy controls participated in this study.

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Post-traumatic stress disorder (PTSD) is a debilitating psychiatric disorder. It can be difficult to discern the symptoms of PTSD and obtain an accurate diagnosis. Different magnetic resonance imaging (MRI) modalities focus on different aspects, which may provide complementary information for PTSD discrimination.

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To realize the accurate positioning and quantitative volume measurement of tumor in head and neck tumor CT images, we proposed a level set method based on augmented gradient. With the introduction of gradient information in the edge indicator function, our proposed level set model is adaptive to different intensity variation, and achieves accurate tumor segmentation. The segmentation result has been used to calculate tumor volume.

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Objective: To investigate mutational spectrum and frequency of the mitochondrial 12S rRNA gene in Chinese subjects with aminoglycoside-induced and non-syndromic hearing loss.

Methods: Total of 456 subjects with non-syndromic hearing loss were recruited from seven schools for deaf-mutes in Zhejiang province. Genomic DNA was extracted from the whole blood, and then the DNA fragment was amplified spanning the 12S rRNA gene, followed by sequencing and analyzed.

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