Alzheimer's disease (AD) is a progressive neurodegenerative disease. Early detection and intervention are crucial in preventing the progression of AD. To achieve efficient and scalable AD auto-detection based on structural Magnetic Resonance Imaging (sMRI), a lightweight neural network using multi-slice sMRI is proposed in this paper.
View Article and Find Full Text PDFComput Biol Med
March 2023
Alzheimer's disease (AD) is the most common form of dementia and there is no effective treatment currently. Using artificial intelligence technology to assist the diagnosis and intervention as early as possible is of great significance to delay the development of AD. Structural Magnetic Resonance Imaging (sMRI) has shown great practical values on computer-aided AD diagnosis.
View Article and Find Full Text PDFMagnetic resonance imaging (MRI) is by nature a multi-modality technique that provides complementary information about different aspects of diseases. So far no attempts have been reported to assess the potential of multi-modal MRI in discriminating individuals with and without migraine, so in this study, we proposed a classification approach to examine whether or not the integration of multiple MRI features could improve the classification performance between migraine patients without aura (MWoA) and healthy controls. Twenty-one MWoA patients and 28 healthy controls participated in this study.
View Article and Find Full Text PDFPost-traumatic stress disorder (PTSD) is a debilitating psychiatric disorder. It can be difficult to discern the symptoms of PTSD and obtain an accurate diagnosis. Different magnetic resonance imaging (MRI) modalities focus on different aspects, which may provide complementary information for PTSD discrimination.
View Article and Find Full Text PDFSheng Wu Yi Xue Gong Cheng Xue Za Zhi
August 2015
To realize the accurate positioning and quantitative volume measurement of tumor in head and neck tumor CT images, we proposed a level set method based on augmented gradient. With the introduction of gradient information in the edge indicator function, our proposed level set model is adaptive to different intensity variation, and achieves accurate tumor segmentation. The segmentation result has been used to calculate tumor volume.
View Article and Find Full Text PDFZhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
December 2012
Objective: To investigate mutational spectrum and frequency of the mitochondrial 12S rRNA gene in Chinese subjects with aminoglycoside-induced and non-syndromic hearing loss.
Methods: Total of 456 subjects with non-syndromic hearing loss were recruited from seven schools for deaf-mutes in Zhejiang province. Genomic DNA was extracted from the whole blood, and then the DNA fragment was amplified spanning the 12S rRNA gene, followed by sequencing and analyzed.