Type I and type II infection status and their impact on gastrin and pepsinogen level in a gastric cancer prevalent area.

Background: Type I () infection causes severe gastric inflammation and is a predisposing factor for gastric carcinogenesis. However, its infection status in stepwise gastric disease progression in this gastric cancer prevalent area has not been evaluated; it is also not known its impact on commonly used epidemiological gastric cancer risk markers such as gastrin-17 (G-17) and pepsinogens (PGs) during clinical practice.

Aim: To explore the prevalence of type I and type II infection status and their impact on G-17 and PG levels in clinical practice.

Corilagin attenuates aerosol bleomycin-induced experimental lung injury.

Idiopathic pulmonary fibrosis (IPF) is a progressing lethal disease with few clinically effective therapies. Corilagin is a tannin derivative which shows anti-inflammatory and antifibrotics properties and is potentiated in treating IPF. Here, we investigated the effect of corilagin on lung injury following bleomycin exposure in an animal model of pulmonary fibrosis.