Discovery of antibacterial diketones against gram-positive bacteria.

The rapid rise of antibiotic resistance calls for the discovery of new antibiotics with distinct antibacterial mechanisms. New target mining is indispensable for developing antibiotics. Plant-microbial antibiotics are appealing to underexplored sources due to a dearth of comprehensive understanding of antibacterial activity and the excavation of new targets.

Flexible and stretchable implantable devices for peripheral neuromuscular electrophysiology.

The peripheral nervous and muscular system, a cornerstone of human physiology, plays a pivotal role in ensuring the seamless functioning of the human body. This intricate network, comprising nerves and muscles extending throughout the body, is essential for motor control, sensory feedback, and the regulation of autonomic bodily functions. The qualified implantable peripheral interface can accurately monitor the biopotential of the target tissue and conduct treatment with stimulation, enhancing the human-machine interaction and new achievements in disease cure.

Decision tree models for the estimation of geo-polymer concrete compressive strength.

The green concretes industry benefits from utilizing gel to replace parts of the cement in concretes. However, measuring the compressive strength of geo-polymer concretes (CSGPoC) needs a significant amount of work and expenditure. Therefore, the best idea is predicting CSGPoC with a high level of accuracy.

Water-responsive supercontractile polymer films for bioelectronic interfaces.

Connecting different electronic devices is usually straightforward because they have paired, standardized interfaces, in which the shapes and sizes match each other perfectly. Tissue-electronics interfaces, however, cannot be standardized, because tissues are soft and have arbitrary shapes and sizes. Shape-adaptive wrapping and covering around irregularly sized and shaped objects have been achieved using heat-shrink films because they can contract largely and rapidly when heated.

Adhesive Carbon Paste Electrode for Convenient and Long-term Electrocardiogram Monitoring: A Pilot Study.

Long-term electrocardiogram (ECG) monitoring is an important and widely-used technique in the clinic that helps with the diagnosis of possible diseases that cannot be detected in a short time monitoring. However, the clinically used electrode needs conductive gel to reduce the impedance between the skin and the electrodes, which easily causes the possibility of allergy. Moreover, as the conductive gel becomes dry, the signal's quality will decrease accordingly.

Cloning, sequencing, expression, and purification of aspartic proteases isolated from two human Demodex species.

Aspartic proteases (ASPs) are important hydrolases for parasitic invasion of host tissues or cells. This was the first study on Demodex ASP. First, the complete coding sequence (CDS) was amplified, cloned and sequenced.

Solvent-Free and Skin-Like Supramolecular Ion-Conductive Elastomers with Versatile Processability for Multifunctional Ionic Tattoos and On-Skin Bioelectronics.

The development of stable and biocompatible soft ionic conductors, alternatives to hydrogels and ionogels, will open up new avenues for the construction of stretchable electronics. Here, a brand-new design, encapsulating a naturally occurring ionizable compound by a biocompatible polymer via high-density hydrogen bonds, resulting in a solvent-free supramolecular ion-conductive elastomer (SF-supra-ICE) that eliminates the dehydration problem of hydrogels and possesses excellent biocompatibility, is reported. The SF-supra-ICE with high ionic conductivity (>3.

Hairy-Skin-Adaptive Viscoelastic Dry Electrodes for Long-Term Electrophysiological Monitoring.

Long-term epidermal electrophysiological (EP) monitoring is crucial for disease diagnosis and human-machine synergy. The human skin is covered with hair that grows at an average rate of 0.3 mm per day.

Structured electroplating sludge derived membrane for one-step removal of oil, metal ions, and anions from oil/water emulsions.

The effective simultaneous treatment of hazardous waste sludge and complex oil/water emulsions in one way is urgently desired but still a challenging issue. Herein, this work for the first time presents a green and efficient strategy to fabricate an electroplating sludge (ES) derived multifunctional self-supporting membrane for the one-step removal of emulsified oils, soluble metal ions, and anions in complex oily wastewater. Due to low cost of ES and sustainability of the solvent selected in fabrication process, the large-scale application of the membrane is easily to promote.

Facile fabrication of solar-heating and Joule-heating hyperelastic MXene-modified sponge for fast all-weather clean-up of viscous crude oil spill.

Developing rational sorbent for viscous crude oil clean-up is still a daunting challenge, which requires rapid oil-uptake capability and scalable fabrication process. Herein, a heatable hydrophobic sponge sorbent (H-MXene/PVA/MS) with excellent light/Joule-heating performances was fabricated by a simple and feasible top-down approach. MXene nanosheets firmly coated on the substrate skeleton gave the sorbent outstanding ability to convert solar/electricity into heat rapidly due to the localized surface plasmon resonance (LSPR) effect and ultrahigh metallic conductivity.

Laminated MXene Foam/Cellulose@LDH Composite Membrane with Efficient EMI Shielding Property for Asymmetric Personal Thermal Management.

Facing the increasingly complex and deteriorated environment, people's thermal comfort and health requirements are expanding. Therefore, wearable materials with integrated functions have progressed rapidly due to the fair compatibility for various functions and precise regulation. In this work, a laminated MXene foam/cellulose@LDH composite membrane was fabricated via a facile process consisting of in situ growth, vacuum filtration, and foaming for asymmetrical personal thermal management and electromagnetic interference shielding.

Ultrapermeable and Wet-Adhesive Monolayer Porous Film for Stretchable Epidermal Electrode.

Noninvasive electrophysiological signal monitoring is significant for health care and scientific research. The simultaneous achievement of wet adhesion, stretchability, breathability, and low contact impedance is highly recommended in the epidermal electrode but still challenging. In this work, a monolayer porous film electrode with a pore size and wall thickness of less than ∼10 μm is fabricated via the breath figure method (BFM) and metal sputtering, and it was subsequently applied using epidermal electrophysiological monitoring.

Solar-heating superhydrophobic modified melamine sponge for efficient recovery of viscous crude oil.

Developing self-heating sorbents for rapid clean-up of viscous oil spills by using clean solar energy is attracting attention. Still, simple and scalable fabrication approaches of solar-heating sorbents remain challenging. Herein, a facile and practical modification strategy was presented to develop a solar-heating modified melamine sponge (rGO/CNT/MS) by dip-coating layer-by-layer (LBL) electrostatic assembly of GO and CNT with opposite charges onto MS skeleton followed by thermal reduction, without any complicated microfabrication and hydrophobic modification processes.

Recyclable structured toxic industrial nickel-containing sludge for efficient anionic contaminant adsorption.

Safe, efficient, and simultaneous treatment of toxic industrial sludge and anionic contaminant crisis in one route still remains a persistent global challenge. Herein, we proposed a facile waste-control-waste conceptual design strategy to develop low-cost and high-performance sludge-based adsorbent for not only recycling of toxic waste nickel-containing sludge (NCS) but for the efficient removal of anionic contaminants in wastewater. The as-designed Ni-Al layered double oxides/calcined NCS (Ni-Al LDOs/CNCS) (216.

Towards Optimizing the Quality of Long-Term Physiological Signals Monitoring by Using Anhydrous Carbon Paste Electrode.

Long-term physiological signal monitoring is very important for the diagnosis of health conditions that occur randomly and cannot be easily detected by a short period of a hospital visit. However, the conventional wet electrodes suffered from the problem of signal quality degradation due to the gradual dehydration of the conductive gel. An anhydrous carbon paste electrode (CPE) constructed by a composite of carbon black and polydimethylsiloxane was proposed to enable long-term physiological signal monitoring without signal quality degradation as time elapses.

Toxic waste sludge derived hierarchical porous adsorbent for efficient phosphate removal.

Global effective treatment of phosphorus crisis and toxic waste sludge in one way is urgently needed but still insufficient due to single function, environmental damage, and complicated fabrication process. Herein, we proposed a facile, low-cost, and sustainable strategy to fabricate NiAl layered double oxides/nickel-containing sludge (LDOs/NCS) adsorbent using toxic NCS as raw material via two-step method including hydrothermal process and calcination. The as-designed hierarchical porous adsorbent with large specific surface area and pore volume exhibited excellent adsorption properties towards phosphate.

Structured sludge derived multifunctional layer for simultaneous separation of oil/water emulsions and anions contaminants.

The effective treatment of complex oily wastewater is of great significance but still a considerable challenge, since single-function, expensive reagents, and complicated process have emerged as shackles for practical applications. Herein, with the objective to waste-control-waste, we proposed a facile and sustainable strategy to fabricate a low-cost multifunctional layer from hazardous waste aluminum sludge (WAS) for complex oily wastewater management. The as-designed layered double oxides/WAS (LDOs/WAS) layer with three-dimensional (3D) hierarchical rough surface exhibited excellent underwater superoleophobicity even under corrosive conditions and low adhesion to oil without any chemical modification reagent treatment.

Mechanical sensors based on two-dimensional materials: Sensing mechanisms, structural designs and wearable applications.

Compared with bulk materials, atomically thin two-dimensional (2D) crystals possess a range of unique mechanical properties, including relatively high in-plane stiffness and large bending flexibility. The atomic 2D building blocks can be reassembled into precisely designed heterogeneous composite structures of various geometries with customized mechanical sensing behaviors. Due to their small specific density, high flexibility, and environmental adaptability, mechanical sensors based on 2D materials can conform to soft and curved surfaces, thus providing suitable solutions for functional applications in future wearable devices.

Recent advances in flexible and wearable sensors for monitoring chemical molecules.

In recent years, real-time health management has received increasing attention, benefiting from the rapid development of flexible and wearable devices. Conventionally, flexible and wearable devices are used for collecting health data such as electrophysiological signals, blood pressure, heart rate, The monitoring of chemical factors has shown growing significance, providing the basis for the screening, diagnosis, and treatment of many diseases. Nowadays, in order to understand the health status of the human body more comprehensively and accurately, researchers in the community have started putting effort into developing wearable devices for monitoring chemical factors.

Electrical Failure Mechanism in Stretchable Thin-Film Conductors.

Stretchable thin-film conductors are basic building blocks in advanced flexible and stretchable electronics. Current research mainly focuses on strategies to improve stretchability and widen the range of applications of stretchable conductors. However, stability should not be neglected, and the electrical failure mode is one of the most common stability issues that determines the current range and duration in a circuit.

Programmable living assembly of materials by bacterial adhesion.

The field of engineered living materials aims to construct functional materials with desirable properties of natural living systems. A recent study demonstrated the programmed self-assembly of bacterial populations by engineered adhesion. Here we use this strategy to engineer self-healing living materials with versatile functions.

A Pilot Study on Long-term Physiological Signal Monitoring using Anhydrous Viscoplastic Electrodes.

Electrocardiography (ECG) and Electromyogram (EMG) are widely used to help physicians to diagnose various diseases. Besides, long-term physiological signals monitoring is of great significance for circumstances where certain diseases may not be observed in short-term monitoring. At present, wet electrodes are widely used in the clinic and are considered as a standard method to acquire physiological signals in high fidelity.

Easily Fabricated Low-Energy Consumption Joule-Heated Superhydrophobic Foam for Fast Cleanup of Viscous Crude Oil Spills.

Effective cleanup of viscous crude oil spills remains a persistent and crippling challenge. Herein, this work presents a Joule-heated superhydrophobic flower-like Cu(POOH)(PO)·7HO-coated copper foam (SHB-CF@CP) for rapid cleanup of viscous crude oil spills via a facile strategy. The SHB-CF@CP shows outstanding water repellency and excellent stability of hydrophobicity in harsh environments.

UBTF facilitates melanoma progression via modulating MEK1/2-ERK1/2 signalling pathways by promoting GIT1 transcription.

Background: UBTF is an HMGB-box DNA binding protein and a necessary Pol I/Pol II basal transcription factor. It has been found that UBTF involves in carcinogenesis and progression of a few cancers. Nevertheless, the the biological function and potential molecular mechanism of UBTF in melanoma are still not clear and need to be clarified.