Relationship Between the ApoE Gene Polymorphism and Type 2 Diabetes Mellitus Complications.

Apolipoprotein E (ApoE) polymorphisms are associated with type 2 diabetes mellitus (T2DM) and its complications, but studies have shown conflicting results. To examine the relationship of ApoE gene polymorphisms with T2DM and its complications. This case-control study of patients with T2DM was conducted between June 2016 and July 2019.

Long-Term Alcohol-Induced Activation of Mammalian Target of Rapamycin is a Key Risk Factor of Epilepsy.

BACKGROUND The aim of this study was to determine whether activation of mammalian target of rapamycin (mTOR) is a key epileptogenic mechanism in the development of alcohol-related seizure. MATERIAL AND METHODS C57BL/6 mice were administered 10% ethanol in drinking water for 9 weeks. Video-electroencephalography (EEG) monitoring was then used to assess seizure frequency after alcohol and rapamycin treatment.

Automics: an integrated platform for NMR-based metabonomics spectral processing and data analysis.

Background: Spectral processing and post-experimental data analysis are the major tasks in NMR-based metabonomics studies. While there are commercial and free licensed software tools available to assist these tasks, researchers usually have to use multiple software packages for their studies because software packages generally focus on specific tasks. It would be beneficial to have a highly integrated platform, in which these tasks can be completed within one package.