Publications by authors named "Qinyao Wang"
Wogonin is a natural flavone compound from the plant Scutellaria baicalensis, which has a variety of pharmacological activities such as anti-cancer, anti-virus, anti-inflammatory, and immune regulation. However, the potential mechanism of wogonin remains unknown. This study was to confirm the molecular mechanism of wogonin for acute monocytic leukemia treatment, known as AML-M5.
View Article and Find Full Text PDFIntroduction: Abnormal alternative splicing (AS) contributes to aggressive intrahepatic invasion and metastatic spread, leading to the high lethality of hepatocellular carcinoma (HCC).
Objectives: This study aims to investigate the functional implications of UPF3B-S (a truncated oncogenic splice variant) in HCC metastasis.
Methods: Basescope assay was performed to analyze the expression of UPF3B-S mRNA in tissues and cells.
Article Synopsis
- Gene variants, particularly in the SLC26A4 gene, account for over half of nonsyndromic hearing loss, with specific variants like c.919-2A > G being prevalent in East Asian populations.
- A study involving 1167 patients from Southwest China's Yunnan examined the frequency of two specific SLC26A4 variants among Han Chinese and ethnic minorities, revealing that the c.919-2A > G variant was more common in Han Chinese than in ethnic minorities.
- Overall, the study found that both variants had lower frequencies in the Yunnan cohort compared to other regions in China, contributing valuable data to the genetic profile of hearing loss in these populations.
Ovarian cancer is a gynecological cancer from which it is difficult to be completely cured. It is common to use regimens as an effective treatment for ovarian cancer, but these inevitably bring serious side effects. New treatment strategies and special drugs are needed to improve the prognosis of patients.
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