Reliability and validity of the international dementia alliance schedule for the assessment and staging of care in China.

Background: Clinical and social services both are important for dementia care. The International Dementia Alliance (IDEAL) Schedule for the Assessment and Staging of Care was developed to guide clinical and social care for dementia. Our study aimed to assess the validity and reliability of the IDEAL schedule in China.

Efficacy and safety of a novel acetylcholinesterase inhibitor octohydroaminoacridine in mild-to-moderate Alzheimer's disease: a Phase II multicenter randomised controlled trial.

Background: inhibition of acetylcholinesterase (AChE) has been a effective treatment for Alzheimer's disease (AD). Octohydroaminoacridine, a new AChE inhibitor, is a potential treatment for AD.

Method: we conducted a multicenter, randomised, double blind, placebo-controlled, parallel-group Phase II clinical trial to investigate the effects of octohydroaminoacridine in patients with mild-to-moderate AD.

A survey of sleep quality in patients with 13 types of mental disorders.

Objective: To investigate the sleep characteristics of a community sample of patients with 13 types of mental disorders.

Method: Subjects aged 18 years and older were sampled from the Epidemiologic Sites Survey of Mental Illness at a mental health center in Hebei Province, Baoding, China, from October 2004 to March 2005. The study group included 1,874 subjects who met the diagnostic criteria of 13 types of mental disorders according to the Structured Clinical Interview for DSM-IV-TR Axis I Disorders-Patient Edition (major depressive disorder, panic disorder, generalized anxiety disorder, posttraumatic stress disorder, dysthymic disorder, bipolar affective disorder, somatoform disorder, obsessive-compulsive disorder, specific phobia, schizophrenia, adjustment disorder, social phobia, and alcohol abuse and dependence.

Epidemiological survey of mental disorders in the people aged 18 and older in Hebei Province.

Objective: To describe the time point prevalence and distribution of all types of mental disorders in Hebei Province.

Methods: From October 2004 to March 2005, stratified multi-stage cluster randomization was used to identify 24,000 subjects ≥18 years of age in Hebei Province. An expanded version of the General Health Questionnaire (GHQ-12) was used to identify subgroups of subjects at high, moderate and low risk of having a mental disorder, then psychiatrists determined their diagnoses by administering a structured psychiatric examination (SCID) that employs Diagnostic and Statistical Manual of Mental Disorder (DSM-IV).