Clinical features, radiological findings and prognosis of microscopic polyangiitis with interstitial lung disease: a retrospective matched control study.

Background: The association between interstitial lung disease (ILD) and microscopic polyangiitis (MPA) has received increasing attention in recent years. However, there are still no studies comparing clinical characteristics and prognoses between MPA-ILD patients and patients with ANCA-negative ILDs. Therefore, the purpose of this study was to analyse a group of patients presenting MPA-ILD matched with patients exhibiting ANCA-negative ILDs to identify differences in their clinical characteristics and survival.

PAI-1 Gene Polymorphism Was Associated with an Increased Risk of Allergic Diseases: Evidence from a Meta-Analysis of 14 Case-Control Studies.

Introduction: In recent years, many studies have focused on the association between plasminogen activator inhibitor (PAI)-1 gene 4G/5G polymorphism and risk of allergic diseases, but the results have been inconclusive.

Objective: We conducted this meta-analysis to study the exact relationship between PAI-1 polymorphism and susceptibility to allergic diseases.

Methods: All eligible studies were determined by an electronic literature search.