Publications by authors named "Qingyun Fan"

Background: Despite patients with thyroid dysfunction show obvious abnormal hemostatic indicators in the peripheral blood, the current research on whether and how subclinical hypothyroidism (SCH) influence hemostatic function (the coagulation and fibrinolytic system) still remains controversial.

Objective: We conducted this study to evaluate how SCH influence on the coagulation and fibrinolytic system in human body.

Methods: Prior to March 2022, Web of Science, Embase, PubMed, WanFang, CNKI data and reference lists were searched to identify eligible researches.

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The stoichiometric characteristics of water-soluble ions (WSIs) in PM, which can be used as an indicator socioeconomic development level, are mostly depending on the sources and formation mechanism of PM. This work presents the stoichiometric characteristics and socioeconomic linkage of WSIs in PM from a resource-dependent city. The relationship between NO/SO and car parc indexes the contribution of mobile emission source.

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Air pollution has been considered as one of the most important factors associating with various birth outcomes. However, the seasonal response of maternal comorbidities effects associated with air pollution has not been investigated, especially in the city with distinguish seasonal pattern and long heating seasons. In this work, 69,945 live births were investigated from 2013 to 2016, and the seasonal relationship between air pollution and preterm birth and low birth weight were assessed, as well as the synergism of maternal comorbidities.

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To interpret the relationship of the seasonal pattern of air pollution exposure associated with increased risk of congenital anomalies (CA) and the trimester-specific effects. In this work, 55,428 hospital records with 847 doctor-diagnosed CA from July 2013 to December 2016 were collected in Hohhot, China. Maternal exposure to critical air pollutants (SO, CO, PM, O, NO and PM) were estimated using an inverse distance weighted (IDW) method on the basis of the ambient air quality monitoring stations.

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Objective: To study the regulation of sporulation controlled by two-component system (TCS) YvcPQ.

Methods: β-galactosidase experiment was used to verify the regulation of YvcP on kapD expression; bacterial one-hybrid assay, EMSA and RT-qPCR were applied to study the regulation of AbrB on yvcPQ expression; markerless gene deletion coupled with spore count was used to reveal the influence of yvcPQ and kapD expressions on sporulation.

Results: transcriptional regulator AbrB up-regulated the expression of yvcPQ; YvcP promoted the expression of kapD to inhibit sporulation.

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YvqEC is one of the two-component signal transduction systems that may respond to cell envelope stress and enable cells to adjust multiple cellular functions. It consists of a histidine kinase YvqE and a response regulator YvqC. In this study, we separately constructed a single gene mutant ΔyvqE and a double gene mutant ΔyvqEC in Bacillus thuringiensis BMB171 through a homing endonucleases I-SceI mediated markerless gene deletion method.

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Objective: The purpose of the study was to evaluate the clinical effects of the Shenzhu Tiaopi granule (SZTP) combined with a lifestyle intervention in patients with impaired glucose tolerance (IGT), who also had a spleen deficiency and damp overabundance syndrome (SDDOS).

Methods: After a one-month washout period, a total of 514 patients were randomly assigned to the control (lifestyle intervention) and experimental (SZTP plus lifestyle intervention) groups, with 257 patients in each group. Patients in the control group received the lifestyle intervention (diet and exercise) for 12 months, while the patients in the experimental group were treated with SZTP plus the lifestyle intervention for 12 months.

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The concentrations of Cu, Pb, Zn and Cd were measured in water and sediment to determine their distribution characteristics and potential ecological risks of the Lake Dalinouer. The results revealed that the dominate form of Cu, Pb, Cd and Zn in surface sediments respectively were organic sulfides, Fe-Mn oxides, carbonates and Fe-Mn oxides, with a mean content of 4.28mgkg(-1), 0.

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This paper analyses the contents and species distributions of rare earth elements (REEs) in the water-suspended particulate-sediment system of the Baotou section of the Yellow River, China, with known anthropogenic REE input from industrial discharges. The major forms of REEs were suspended and dissolved in the mainstream and the tributaries of the Baotou section, respectively. The concentrations of the dissolved and suspended REEs had the same trends in the overlying water along the mainstream, which increased from the Seqi section (site A) to the mouth of the Sidaosha River (site D), reaching a maximum value at site D, and tending to decrease thereafter.

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The expression of surface fractal dimension (SFD) for size fractions of the Yellow River sediment was deduced. Based on the expression, the SFD value of different size fractions of the sediment was calculated. The SFD value of the sediment in the Baotou section of the Yellow River is 1.

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Lake Wuliangsuhai is one of the representative inland freshwater lakes in grassland areas of China, and its shrinking and eutrophication is becoming more serious. The study on the ecological and environmental effects of the shrinking and eutrophication revealed that the total nitrogen (TN) content in the surface sediment of the lake had an obvious differentiation both in longitudinal and in latitudinal direction, and had a significant correlation with organic matter content. The mean C/N ratio of the sediment ranged from 12.

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As a whole of water column, suspended matter and surface sediment in the mainstream and the branch taking up industry wastewater, speciation and distribution characters of rare earth elements (REEs) were investigated systemically in the Baotou section of the Yellow River. This study shows that rare earth elements in the mainstream of the Baotou section of the Yellow River mainly exist in suspended particles, and the dissolved contents are in extremely minute quantities. REEs mainly exist in dissolved particles in the branch taking up industry wastewater, and suspended sigma REE and dissolved sigma REE are obviously higher than those in the mainstream.

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