Publications by authors named "Qingying Lan"
Dystrophic epidermolysis bullosa (DEB) is a rare, but severe, subtype of epidermolysis bullosa. It is characterized mainly by blisters and miliary rashes of the skin, while oral mucosa-dominated cases are extremely rare. Here, we report the characteristics of oral mucosa lesions in a Chinese familial case of DEB with a novel compound heterozygous COL7A1 mutation.
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- Proliferative verrucous leukoplakia (PVL) has a high malignant transformation rate of 43.87% to 65.8%, making it the most aggressive oral potentially malignant disorder; this study aims to analyze its features and associated risks.
- Over a decade, the study evaluated 36 PVL patients, predominantly females, revealing that the verrucous lesion type was most common and that 33.3% developed oral cancer during a follow-up period averaging 47.5 months.
- Key risk factors for malignancy included pain, roughness, diabetes, and cytologic atypia, emphasizing the need for further research despite no significant difference in malignant transformation rates between treated and
Background: Oral squamous cell carcinoma (OSCC) is one of the most common malignant tumours with increasing incidence, and oral leukoplakia (OLK) has a strong tendency to undergo malignant transformation. The oral microbiota may influence oral cancer progression, but the salivary bacterial composition and functional changes in OSCC and OLK have not been comprehensively elucidated. Therefore, we compared salivary bacteria in OLK and OSCC patients with healthy controls (HC).
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