Magnetopyrite FeS modified with N/S-doped carbon as a synergistic electrocatalyst for lithium-sulfur batteries.

Rational design of effective cathode host materials is an effective way to solve the problems of serious shuttle and slow conversion of polysulfides in lithium-sulfur batteries (LSBs). However, the redox reaction of sulfur differs from conventional "Rocking chair" type batteries and involves a cumbersome phase transition process, so a single-component catalyst cannot consistently and steadily enhance the reaction rate throughout the redox process. In this work, a hybrid composed of magnetopyrite FeS catalyst-modified with N/S-doped porous carbon spheres (FeS@NSC) is proposed as a novel sulfur host to synergistically promote the adsorption and redox catalysis conversion of polysulfides.

rGO@TiO Schottky heterojunction for enhanced bidirectional catalysis in polysulfide conversion.

The shuttling and sluggish conversion kinetics of lithium polysulfides (LiPSs) lead to poor cycling performance and low energy efficiency in lithium-sulfur batteries (LSBs). In this work, a hierarchically structured nanocomposite, synthesized through a surfactant-directed hydrothermal growth following dopamine-protected pyrolysis, serves as a bidirectional catalyst for LSBs. This nanocomposite comprises N-doped reduced graphene oxide (rGO) nanosheets anchored with uniformly distributed TiO nanoparticles via interfacial N-Ti and C-Ti bonding, resulting in the formation of abundant 2D/0D Schottky heterojunctions (rGO/TiO).

Nitrogen-doped hollow carbon@tin disulfide as a bipolar dynamic host for lithium-sulfur batteries with enhanced kinetics and cyclability.

Lithium-sulfur batteries (LSBs) are promising next-generation electrochemical energy storage systems owing to high theoretical specific capacity (1675 mAh/g) and low cost. However, the shuttling effect of soluble polysulfides with slow conversion kinetics has deferred their commercial applications. The feasible design and synthesis of composite cathode hosts offer a promise solution to improving their electrochemical performances.

15-hydroxy-6,12-epoxy-7,10H,11H-spiroax-4-ene-12-one sensitizes rectal tumor cells to anti-PD1 treatment through agonism of CD11b.

Purpose: Although immunotherapies have resulted in durable clinical responses, not all tumor types have seen substantial benefit. Extensive recruitment and accumulation of immunosuppressive myeloid cells into the tumor tissues has been postulated as a major mechanism of resistance to immunotherapies. Strategies targeting on single immunosuppressive cell type, in combination with checkpoint inhibitors, have resulted in promising outcomes in animal studies.

Reversible posterior leukoencephalopathy syndrome induced by apatinib: a case report and literature review.

Reversible posterior leukoencephalopathy syndrome (RPLS) is a rare clinical-radiologic syndrome. There are reports that RPLS may be associated with cancer therapy including some chemotherapy drugs and antiangiogenic drugs. This paper reported a case of RPLS induced by apatinib, a vascular endothelial growth factor receptor 2 (VEGFR-2) tyrosine kinase inhibitor.

ING5 inhibits epithelial-mesenchymal transition in breast cancer by suppressing PI3K/Akt pathway.

Epithelial-mesenchymal transition (EMT) is a crucial step in tumor progression and has an important role during cancer invasion and metastasis. The proteins of the inhibitor of growth (ING) candidate tumor suppressor family are involved in multiple cellular functions such as cell cycle regulation and apoptosis. ING5 is a member of the family.

Systematic analysis of gene expression and molecular interactions in cardiac and non-cardiac gastric carcinomas.

Background/aims: : This study aims to comparing the gene expression profiles and molecular interactions among gastric cardiac adenocarcinomas (GCA), gastric noncardiac adenocarcinomas (GNCA) and their adjacent normal tissues.

Methodology: Gene expression profile of GSE29272 was downloaded from Gene expression omnibus. Differentially expressed genes (DEGs) were identified at the cut-off of p-value ≤ 0.