New β-diketone-boron difluoride based near-infrared fluorescent probes for polarity detection.

Two new β-diketone-boron difluoride based near-infrared fluorescent probes 1 and 2 which exhibit polarity sensitivity have been designed and synthesized. Probes 1 and 2 are composed of a β-diketone-boron difluoride moiety as an acceptor unit, and a diethylamino group and a phenolic hydroxyl group as donor units. The long conjugate structures form a "donor-acceptor-donor" configuration, induce intramolecular charge transfer (ICT), and confer near-infrared fluorescence emission and excellent polarity sensitivity.

An ultrasensitive sandwich-type electrochemical immunosensor based on the signal amplification system of double-deck gold film and thionine unite with platinum nanowire inlaid globular SBA-15 microsphere.

A novel thionine unites with platinum nanowire inlaid globular SBA-15 (Pt NWs@g-SBA-15/Thi) not only utilizes as an efficient electrical signal probe but also constitutes an amplifying system with double-deck gold film (D-Au film) have been applied to the fabrication of sandwich-type immunosensor for detecting hepatitis B surface antigen (HBs Ag). The D-Au film can accelerate the electron transfer on the electrode interface due to the tunneling effect between the two Au films and can improve the load capacity of primary antibodies (Ab) because of the good biocompatibility. The Pt NWs@g-SBA-15/Thi with uniform globular morphology not only can effectively reduce the spatial limitation for loading the secondary antibodies (Ab) but also can provide outstanding pore accessibility of guest species from outside and offer catalytically active sites in a large scale.

An ultrasensitive sandwich-type electrochemical immunosensor based on the signal amplification strategy of mesoporous core-shell Pd@Pt nanoparticles/amino group functionalized graphene nanocomposite.

Herein, a novel and sensitive sandwich-type electrochemical immunosensor was fabricated for quantitative monitoring of prostate specific antigen (PSA). The sulfo group functionalized multi-walled carbon nanotubes (MWCNTs-SOH) were used as substrate material to increase the specific surface area and enhance the conductivity of the glassy carbon electrode. Gold nanoparticles (Au NPs) were introduced to enhance the load capacity of the substrate material for primary antibodies (Ab) and accelerate the electron transfer on the electrode interface.

3,7-Dihydr-oxy-3,7-diphenyl-2H,6H-pyrrolo[3,4-f]isoindole-1,5(3H,7H)-dione methanol disolvate.

The asymmetric unit of the title compound, C(22)H(16)N(2)O(4)·2CH(4)O, contains one half-mol-ecule and a methanol solvent mol-ecule. The aromatic ring is oriented at a dihedral angle of 82.91 (3)° with respect to the planar indole ring systems.

1-Phenyl-5-[4-(trifluoro-meth-yl)phen-yl]-pyrazolidin-3-one monohydrate.

In the mol-ecule of the title compound, C(16)H(13)F(3)N(2)O·H(2)O, the two benzene rings are oriented at a dihedral angle of 82.55 (3)° and the pyrazole ring adopts an envelope conformation. In the crystal structure, inter-molecular C-H⋯F hydrogen bonds link the mol-ecules into chains.

2-[Bis(3,5-dimethyl-phen-yl)-phosphor-yl]-propan-2-ol hemihydrate.

In the organic mol-ecule of the title compound, C(19)H(25)O(2)P·0.5H(2)O, the benzene rings are oriented at a dihedral angle of 54.04 (3)°.

(S)-(-)-Methyl 2-(p-tolyl-sulfon-yloxy)-propanoate.

In the title compound, C(11)H(14)O(5)S, there is an intra-molecular C-H⋯O hydrogen bond, for which the C-C-S-O torsion angle involving the acceptor and donor atoms is 2.4 (4)°. The dihedral angle between the benzene ring and the methoxy-carbonyl plane is 52.

2,3,4,6-Tetra-O-acetyl-1-O-(4-methoxy-cinnamo-yl)-β-d-glucopyran-ose.

Mol-ecules of the title compound, C(24)H(28)O(12), are linked by inter-molecular C-H⋯O hydrogen bonds. Bond lengths and angles are normal.

5-(3-Fluoro-phen-yl)-1-phenyl-pyrazolidin-3-one.

In the mol-ecule of the title compound, C(15)H(13)FN(2)O, the phenyl and fluorophenyl rings are oriented at a dihedral angle of 77.92 (3)°. The pyrazolidine ring adopts an envelope conformation.