Transmission dynamics of SARS-CoV-2 Omicron variant infections in Hangzhou, Zhejiang, China, January-February 2022.

Objectives: We aimed to explore the transmission dynamics of the Omicron BA.1.1 variant in an outbreak in China.

Clinical Observation of Ropinirole Hydrochloride in the Treatment of Parkinson's Disease.

Parkinson's disease is a degenerative disease of the nervous system, which is more common in middle-aged and elderly people. Currently, the incidence of PD is increasing. The disease is a degenerative disease, which is irreversible and requires life-long treatment.

Evaluation of the risk of fracture in type 2 diabetes mellitus patients with incretins: an updated meta-analysis.

Introduction: The effect of incretins including dipeptidyl peptidase 4 inhibitors (DPP4-Is) and glucagon-like peptide1 receptor agonists (GLP1-ras) in the treatment of type 2 diabetes increasing the risk of fracture remains controversial. No meta-analysis has been written to discuss this from the prospective interventional studies. The objective was to evaluate the association between the use of incretins and fracture risk.

Potential transmission of SARS-CoV-2 on a flight from Singapore to Hangzhou, China: An epidemiological investigation.

Background: Between January 24, 2020 and February 15, 2020, an outbreak of COVID-19 occurred among 335 passengers on a flight from Singapore to Hangzhou in China. This study aimed to investigate the source of the outbreak and assess the risk of transmission of COVID-19 during the flight.

Method: Using a standardized questionnaire, we collected information on the travelers' demographic characteristics and illness before, during, and after the flight.

Celastrol induces ubiquitin-dependent degradation of mTOR in breast cancer cells.

Background: Celastrol is a major active component of the thunder god vine () used in traditional Chinese medicine to treat chronic inflammatory and autoimmune diseases. Celastrol inhibits PI3K-Akt-mTOR signaling, which is frequently dysregulated in tumors and critical for tumor-cell proliferation and survival, but the underlying mechanisms are still not fully understood. In the present study, we investigated detailed mechanisms of celastrol inhibition of mTOR signaling in breast cancer cells.

Knowledge, attitudes, and practices regarding environmental cleaning among environmental service workers in Chinese hospitals.

We conducted a study using a face-to-face survey to assess knowledge, attitudes, and practices of environmental service workers (ESWs) concerning routine cleaning and disinfection at 3 tertiary hospitals in China. There were 115 (89.1%) respondents who agreed that environmental cleaning can contribute to keep patients safe, whereas 63 (48.

[Impacts of high temperature on maize production and adaptation measures in Northeast China].

Heat stress is one of the major agro-meteorological hazards that affect maize production significantly in the farming region of Northeast China (NFR). This study analyzed the temporal and spatial changes of the accumulated temperature above 30 °C (AT) and the accumulated days with the maximum temperature above 30 °C (AD) in different maize growing phases under global warming. It further evaluated the impacts of extreme heat on maize yield in different regions, and put forward some adaptation measures to cope with heat stress for maize production in NFR.

A randomized, double-blind comparison of the effectiveness of environmental cleaning between infection control professionals and environmental service workers.

The hospital environment is a reservoir for pathogens, and environmental service workers (ESWs) play an important role in infection prevention. A randomized, double-blind comparison was carried out in a 23-bed intensive care unit of a traditional Chinese medical-Western medical hospital. Aerobic colony counts (ACC) and methicillin-resistant Staphylococcus aureus (MRSA) were used to compare the effectiveness of environmental cleaning between infection control professionals and ESWs.

[Screening of the aerobic simultaneous denitrobacteria and its denitrification characteristics].

To screen aerobic heterotrophic denitrifying bacteria from various samples and detect metabolites quantitatively during their denitrification process. The bacteria were screened by limit dilution and crossed separation. Nitrate and nitrite were determined using phenol disulfonic acid and N-(1-naphthyl)-ethylene diamine by ultraviolet spectrophotometry.

The relationship between hand area and hand contamination.

Although the number of colony-forming units (CFUs) on the hands of health care workers (HCWs) is a critical measurement in research studies of hand contamination, few studies have investigated the correlation between hand area and CFU count. In the present study, we calculated the area and measured the numbers of CFU on the right hand of 197 HCWs. Our data indicate that close relationship between hand area and CFU count.

Laribacter hongkongensis isolated from a patient with community-acquired gastroenteritis in Hangzhou City.

We describe the isolation of Laribacter hongkongensis in Hangzhou City, People's Republic of China. One strain of bacterium, named LHHZ242, had many of the same phenotypic and genotypic characteristics as Laribacter hongkongensis described in previous publications. This discovery proves that Laribacter hongkongensis is also associated with community-acquired gastroenteritis outside Hong Kong.

Excretion and detection of SARS coronavirus and its nucleic acid from digestive system.

Aim: To study whether severe acute respiratory syndrome coronavirus (SARS-CoV) could be excreted from digestive system.

Methods: Cell culture and semi-nested RT-PCR were used to detect SARS-CoV and its RNA from 21 stool and urine samples, and a kind of electropositive filter media particles was used to concentrate the virus in 10 sewage samples from two hospitals receiving SARS patients in Beijing in China.

Results: It was demonstrated that there was no live SARS-CoV in all samples collected, but the RNA of SARS-CoV could be detected in seven stool samples from SARS patients with any one of the symptoms of fever, malaise, cough, or dyspnea, in 10 sewage samples before disinfection and 3 samples after disinfection from the two hospitals.

Concentration and detection of SARS coronavirus in sewage from Xiao Tang Shan Hospital and the 309th Hospital.

The transmission of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is associated with close contact to SARS patients and droplet secretions of those patients. The finding of positive RT-PCR results from stools of SARS patients suggests that stools of SARS patients or sewage containing stools of patients could transmit SARS-CoV. We used a novel style of electropositive filter media particle to concentrate the SARS-CoV from the sewage of two hospitals receiving SARS patients in Beijing.

Study on the resistance of severe acute respiratory syndrome-associated coronavirus.

In this study, the persistence of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) was observed in feces, urine and water. In addition, the inactivation of SARS-CoV in wastewater with sodium hypochlorite and chlorine dioxide was also studied. In vitro experiments demonstrated that the virus could only persist for 2 days in hospital wastewater, domestic sewage and dechlorinated tap water, while 3 days in feces, 14 days in PBS and 17 days in urine at 20 degrees C.

[Detection of RNA of SARS coronavirus in hospital sewage].

Objective: In order to explore the existence of SARS coronavirus (Co-V) and/or its RNA in sewage of hospitals administered SARS patients.

Methods: A novel electropositive filter was used to concentrate the SARS-CoV from the sewage of two hospitals administered SARS patients in Beijing, including twelve 2,500 ml sewage samples from the hospitals before disinfection, and ten 25,000 ml samples after disinfection; as well as cell culture, RT-PCR and sequencing of gene to detect and identify the viruses from sewage.

Results: There was no live SARS-CoV detected in the sewage in this study.