Publications by authors named "Qingqing Liang"

Aim: To provide a comprehensive overview of situational leadership theory as applied to nursing management, outlining its relevant measurement tools, intervention modalities, and reporting gaps.

Design: A scoping review of the literature was conducted according to the JBI guidelines.

Data Sources: Eight databases were used including PubMed, Embase, CINHAL, Web of Science, CNKI, WanFang, Cqvip, SinoMed.

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Background: Virtual simulation experiment is a vital component of higher education digitalization, emerging from the deep integration of specialty disciplines and information technology. Chinese universities have invested heavily in the construction of virtual simulation experiment projects, and the number of projects is considerably large. However, the popularity and effectiveness of these projects are not satisfactory.

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Article Synopsis
  • The study evaluates the effectiveness of enterovirus A71 (EV-A71) vaccines in reducing hand, foot, and mouth disease (HFMD) cases among children under 5 in China, with analysis based on surveillance data and statistical models.
  • Findings show that between 2017 and 2018, vaccination led to a significant reduction in HFMD incidence, with a relative risk of 0.83, translating to about 298,000 fewer cases.
  • The effectiveness of the vaccine varied by region, was better in areas with higher vaccination coverage (above 20%), and decreased in more densely populated areas, highlighting the need for improved vaccination strategies.
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Background: The coronavirus disease 2019 (COVID-19) continues to threaten human health, and health professionals, including nursing students, usually work in healthcare frontiers with a high risk of infection. Vaccination is currently one of the most effective preventive measures. This study aimed to explore the determinants of COVID-19 vaccine hesitancy in nursing students.

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Hyaline cartilage fibrosis is typically considered an end-stage pathology of osteoarthritis (OA), which results in changes to the extracellular matrix. However, the mechanism behind this is largely unclear. Here, we found that the RNA helicase DDX5 was dramatically downregulated during the progression of OA.

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According to the World Health Organization, chronic obstructive pulmonary disease (COPD) was one of the top ten causes of death worldwide in 2019. The ratio of forced expiratory volume in the first second to forced vital capacity (FEV1/FVC) provides a useful indicator for the diagnosis of COPD. Existing data have demonstrated that cadmium (Cd) exposure is associated with COPD.

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A high-contrast imaging technique for phase objects based on the optical vortex coronagraph (OVC) is proposed. This method offers the unique advantage of background-free imaging due to the introduction of azimuthal phase in the Fourier plane. We employed the OVC method to detect femtosecond laser-induced air plasma and compared it with the classic diffractometry and fluorescent imaging methods.

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Background: The International Agency for Research on Cancer has classified arsenic as a class I carcinogen. Oxidative DNA damage is a typical early precursor to recognized malignancies. The most sensitive early independent marker of oxidative DNA damage is believed to be 8-hydroxy-2 deoxyguanosine (8-OHdG).

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Numerous studies have demonstrated that the stems of have the effect of lowering blood glucose, but the leaves of have seldom been investigated. In this study, we mainly studied the hypoglycemic effect and mechanism of leaves. Initially , male C57BL/6 mice were administered either standard feed (10 kcal% fat) or high-fat feed (60 kcal% fat) along with either normal drinking water or drinking water containing 5 g/L water extract of leaves (EDL) for 16 weeks, and changes in body weight, food intake, blood glucose, etc.

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The processes governing soil bacteria biogeography are still not fully understood. It remains unknown how the importance of environmental filtering and dispersal differs between bacterial taxonomic and functional biogeography, and whether their importance is scale-dependent. We sampled soils across the Tibet plateau, with distances among plots ranging from 20 m to 1550 km.

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SiNPs could induce liver fibrosis, but the mechanism was not completely clear. This study focused on exploring whether long-term SiNPs exposure at human-related exposure dosage could lead to ferritinophagy-mediated ferroptosis and liver fibrosis. , long-term SiNPs exposure induced liver fibrosis inrats accompanied by ferritinophagy and ferroptosis in hepatocytes.

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We report on a spectral splitting effect of the cavity-less lasing emission of nitrogen ions at 391.4 nm pumped by 800-nm femtosecond laser pulses. It was found that with the increase of the nitrogen gas pressure and pump pulse energy, both R and P branches experience spectral splitting.

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Objective: Gut microbiota dysbiosis is closely linked to the pathogenesis of rheumatoid arthritis (RA). We aimed to identify potential probiotic gut microbes that can ameliorate the development of RA.

Design: Microbiota profiling in patients with RA and healthy individuals was investigated via 16S rDNA bacterial gene sequencing and shotgun metagenomics.

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Regeneration of dental pulp the transplantation of dental pulp stem cells (DPSCs) has emerged as a novel therapy for dental pulp necrosis after inflammation and injury. However, providing sufficient oxygen and nutrients to support stem cell survival, self-renewal, and differentiation in the narrow root canal remains a great challenge. In this study, we explored a novel strategy based on cell-laden microfibers for dental pulp regeneration.

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Amorphous silica nanoparticles (SiNPs) have been widely used and mass-producted due to its unique properties. With the life cycle of SiNPs-based products, SiNPs are further released into the air, soil, surface water and sediment, resulting in an increasing risk to humans. SiNPs could enter into the human body through vein, respiratory tract, digestive tract or skin.

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The processes leading to the N lasing are rather complex and even the population distribution after the pump laser excitation is unknown. In this paper, we study the population distribution at electronic and vibrational levels in N driven by ultra-short laser pulse at the wavelengths of 800 nm and 400 nm by using the quantum-mechanical time-domain incoherent superposition model based on the time-dependent Schrödinger equation and the quasi-classical model assuming instantaneous ionization injection described by density matrix. It is shown that while both models provide qualitatively similar results, the quasi-classical instantaneous ionization injection model underestimates the population inversions corresponding to the optical transitions at 391 nm, 423 nm and 428 nm due to the assumption of quantum mixed states at the ionization time.

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Exposure to fine particulate matter (PM ) was associated with an increased incidence of liver metabolic disease. Melatonin has been shown to prevent liver glucolipid metabolism disorders. However, whether melatonin could rescue PM -induced liver metabolic abnormalities remains uncertain.

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Environmental fine particulate matter (PM), which has attracted worldwide attention, is associated with the progression of metabolic-associated fatty liver disease (MAFLD). However, it is unclear whether dietary habit exacerbate liver damage caused by PM. The current study aimed to investigate the combined negative effects of PM and high-fat diet (HFD) on liver lipid metabolism in C57BL/6J mice.

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Pulp loss is accompanied by the functional impairment of defense, sensory, and nutrition supply. The approach based on endogenous stem cells is a potential strategy for pulp regeneration. However, endogenous stem cell sources, exogenous regenerative signals, and neovascularization are major difficulties for pulp regeneration based on endogenous stem cells.

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Growing literatures suggest that silica nanoparticles (SiNPs) exposure is correlated with adverse cardiovascular effects. Cardiac hypertrophy is one of the most common risk factors for heart failure. However, whether SiNPs involved in cardiac hypertrophy and the underlying mechanisms was remained unexploited.

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It has been reported that silica nanoparticles (SiNPs) could cause epithelial-to-mesenchymal transition (EMT), but the specific mechanism is still unclear. Thus, the purpose of this study was to investigate the underlying mechanisms of pulmonary EMT after subacute exposure to SiNPs. The results showed intratracheal instillation of SiNPs increased the pulmonary MDA content, while decreased the activity of SOD and GSH-Px in rats.

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Background: Among various air pollutants, particulate matter (PM) is the most harmful and representative pollutant. Although several studies have shown a link between particulate pollution and obesity, the conclusions are still inconsistent.

Methods: We conducted a systematic review and meta-analysis to pool the effect of PM exposure on obesity.

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Stem cell medicine is gaining momentum in the development of therapy for various end-stage diseases. The search for new seed cells and exploration of their application prospects are topics of interest in stem cell medicine. In recent years, vascular endothelial cells (VECs) have attracted wide attention from scholars.

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Fine particle matter (PM) is recognized as atrial fibrillation (AF) risk factor, especially for older adults. However, studies on the relationship between PM and AF were inconsistent. Herein, we present a systematic review to further assess the correlation between PM and AF in older adults (average age > 50 years old).

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