Publications by authors named "Qingmiao Ge"
Article Synopsis
- Diabetic kidney disease (DKD) is a leading cause of chronic kidney disease, and researchers aimed to find autophagy-related biomarkers for detecting tubulointerstitial injury associated with DKD.
- They analyzed multiple datasets for differentially expressed genes, identifying TRIM22 as a key candidate for further validation using various laboratory techniques.
- TRIM22 showed strong diagnostic potential for DKD, correlating with clinical indicators and indicating its role in kidney injury and autophagy problems in the disease.
Objective: Diabetic kidney disease (DKD) is the most common cause of the end-stage renal disease, which has limited treatment options. Rutaecarpine has anti-inflammatory effects, however, it has not been studied in DKD. Pyroptosis is a newly discovered mode of podocyte death related to inflammation.
View Article and Find Full Text PDFIntegrated Analysis of Ferroptosis and Immunity-Related Genes Associated with Diabetic Kidney Disease.
Diabetes Metab Syndr Obes
November 2023
Purpose: Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease (CKD) worldwide. Elucidation of the molecular mechanisms underlying ferroptosis and immunity in DKD could aid the development of potentially effective therapeutics. This study aimed to perform an integrated analysis of ferroptosis and immune-related differentially expressed mRNAs (DEGs) in DKD.
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