Publications by authors named "Qingmeng Cai"
Article Synopsis
- Antiphospholipid syndrome (APS) is an autoimmune disease that primarily affects younger individuals, but diagnosing it in older patients (60+) can be challenging due to similarities with other thrombosis disorders.
- This study analyzed 161 APS patients, finding that those with elderly-onset APS had higher instances of stroke at diagnosis and more cardiovascular risk factors compared to younger patients.
- Results indicated that elderly-onset APS patients experienced significantly higher rates of mortality over 10 years, highlighting the importance of early recognition and management of their health conditions to improve outcomes.
Objective: There is limited evidence on long-term thrombosis risk in patients with obstetric antiphospholipid syndrome (OAPS). This study aimed to investigate the clinical features and risk factors associated with the first thrombosis in patients with isolated OAPS.
Methods: Data from patients with isolated OAPS were collected.
Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by thrombosis and pregnancy morbidity with the persistent presence of antiphospholipid antibodies (aPLs). Although anticoagulation is the primary treatment for APS, it fails in approximately 20-30% of obstetric APS cases and more than 30% of thrombotic APS cases. Therefore, there is a need for new, targeted treatments beyond anticoagulants.
View Article and Find Full Text PDFObjective: Non-criteria antiphospholipid antibodies (aPLs) increase the diagnostic value for antiphospholipid syndrome (APS) and contribute to better recognition of seronegative APS (SNAPS). However, the clinical utility and the diagnostic value of non-criteria aPLs are inconsistent. This study aimed to investigate the prevalence and clinical significance of 7 non-criteria aPLs in a large APS cohort.
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