Overlooked mechanism of Pb immobilization on montmorillonite mediated by dissolved organic matter in manure compost.

In this study, three kinds of dissolved organic matter (DOM) derived from fresh chicken manure (FDOM), immature compost (IDOM) and mature compost (MDOM) were employed to compare their effects on Pb adsorption onto montmorillonite (MMT). The potential mechanism was revealed by characterization of mineral structure and calculation of interface force. The results demonstrated that the adsorption capacity (q) of Pb onto MMT was decreased by 14.

Effects of biochar underwent different aging processes on soil properties and Cd passivation.

This study aims to determine the efficacy of biochar underwent different aging process including freeze-thaw cycling aging (FB), acidified aging (AB), and microbial aging (MB) on soil physicochemical properties and Cd passivation. The Cd-contaminated soil (3 mg·kg) amended with the three kinds of aging biochar (at 4% w:w) were subjected to 56-day incubation. The application of FB and MB in soil increased the soil pH (0.

Remediation of cadmium contaminated soil by composite spent mushroom substrate organic amendment under high nitrogen level.

Cadmium (Cd) contamination in soil poses a serious threat to ecological environment and crop quality, especially under high nitrogen level. Here, the efficiency of composite organic amendment (spent mushroom substrate and its biochar) on remediation of Cd contaminated soil under high nitrogen level has been studied through a 42 days' soil incubation experiment. The results showed: (i) the application of composite organic amendment minimized the repercussions of high nitrogen and significantly reduced the exchangeable Cd proportion by 28.

Insight into interactions of heavy metals with livestock manure compost-derived dissolved organic matter using EEM-PARAFAC and 2D-FTIR-COS analyses.

Dissolved organic matter (DOM), as the most active ingredient in compost, directly determines the speciation and environmental behavior of HMs. Here, the binding properties of DOM derived from chicken-manure compost (CHM), cow-manure compost (COM) and pig-manure compost (PIM) with HMs were explored by analyses of Fluorescence excitation-emission matrix parallel factor (EEM-PARAFAC) and two-dimensional correlation Fourier transform infrared spectroscopy (2D-FTIR-COS). Results showed that the binding characteristics vary with origin of DOM and type of HMs.

[Overexpression of miR-382-5p Mediated Downregulation of PTEN on Malignant Biological Behavior of Human Glioma U251 Cells].

Objective: To investigate the effect of overexpression of miR-382-5p overexpression on malignant biological behavior of human glioma U251 cells.

Methods: U251 cells were transfected with miR-382-5pmimic. Then miR-382-5p and mRNA levels were detected by reverse transcription-polymerase chain reaction (RT-PCR) after transfection.

Long noncoding RNA ZEB1-AS1 promotes the tumorigenesis of glioma cancer cells by modulating the miR-200c/141-ZEB1 axis.

Long noncoding RNA Zinc Finger E-box-binding homeobox 1 antisense 1 (ZEB1-AS1) reportedly participates in the tumorigenesis of various cancers. However, the clinical significance and biological functions of ZEB1-AS1 in glioma remain virtually unknown. Here, we show that ZEB1-AS1 expression was higher in glioma tissues and cell lines than in corresponding noncancerous samples and primary normal human astrocytes, respectively.

p38 Inhibitor Protects Mitochondrial Dysfunction by Induction of DJ-1 Mitochondrial Translocation After Subarachnoid Hemorrhage.

p38 mitogen-activated protein kinase (MAPK) is a major player in mitochondrial dysfunction after subarachnoid hemorrhage (SAH). Moreover, DJ-1, which responds to oxidative stress and translocates to mitochondria, maintains mitochondrial homeostasis. Although a few studies have demonstrated that DJ-1 indirectly regulates p38 activation, the relationship between DJ-1 and p38 in mitochondrial dysfunction after SAH has not been delineated.

Effect of chemokine CC ligand 2 (CCL2) on α‑synuclein‑induced microglia proliferation and neuronal apoptosis.

The present study aimed to investigate the effect of chemokine CC ligand 2 (CCL2) on α‑synuclein‑mediated microglia proliferation and neuronal apoptosis. Primary cultured microglia and primary neurons were isolated and cultured in vitro. Microglia were divided into four groups: The cells in the control group were treated with an identical amount of PBS, whereas the cells in the CCL2 group were cultured in medium containing 0.

Protein phosphatase 2A regulates the p38 signaling pathway to affect the migration of astrocytes.

The aim of the present study was to investigate the effect and mechanism of protein phosphatase 2A (PP2A) on the migration of astrocytes. The primary astrocytes of neonatal mice were isolated and cultured in vitro, and treated with the PP2A activator D‑erythro‑sphingosine (DES) (activated group) or inhibitor okadaic acid (inhibitory group). The control group was treated with equal amounts of dimethyl sulfoxide.

LncRNA PANDAR as a prognostic marker in Chinese cancer.

Background: LncRNA promoter of CDKN1A antisense DNA damage activated RNA (PANDAR) is reportedly dysregulated in various cancers. We performed this meta-analysis to clarify the efficacy of PANDAR as a prognostic marker in malignant tumors.

Methods: The PubMed, Medline, OVID, Cochrane Library, and Web of Science databases were searched from inception to July 3, 2017.

Long non-coding RNA TUG1 as a potential prognostic biomarker in human cancers: a meta-analysis.

LncRNA taurine upregulated gene 1 (TUG1) is reportedly dysregulated in various cancers. We performed this meta-analysis to clarify the usefulness of TUG1 as a prognostic marker in malignant tumors. The PubMed, Medline, OVID, Cochrane Library, and Web of Science databases were searched from inception to Jan 11, 2017.

NAD(P)H quinone oxidoreductase 1 (NQO1) genetic C609T polymorphism is associated with the risk of digestive tract cancer: a meta-analysis based on 21 case-control studies.

The relationships between the NAD(P)H quinone oxidoreductase 1 (NQO1) C609T polymorphism and the risk of digestive tract (DT) cancer are controversial. Therefore, we performed a meta-analysis to assess the relationships. The databases of Medline, Embase, and WanFang (updated to 15 May 2011) were reviewed.

System review and metaanalysis of the relationships between five metabolic gene polymorphisms and colorectal adenoma risk.

The relationships between some metabolic (including EPHX1, GSTs and NQO1) gene polymorphisms and colorectal adenoma (CRA) risk have been commonly studied, and no conclusions are available up to now. Therefore, we quantitatively studied the relationships by a metaanalysis. The databases of Medline and Embase were retrieved updated to June 15th, 2011.