Epidemiological study of human papillomavirus infection in 105,679 women in Wuhan, China.

Background: Quality assessment of the prevalence and distribution of human papillomavirus (HPV) genotypes could support additional targeted HPV vaccinations. However, the characteristics of HPV infection in Wuhan city are limited in the past decade. We aimed to assess the epidemiology of HPV infection among women and provide a reference for the prevention and treatment of cervical cancer in this region.

Characteristics of catalytic destruction of dichloromethane and ethyl acetate mixture over HPO-RuO/CeO catalyst.

Catalytic destruction is an ascendant technology for the abatement of volatile organic compounds (VOCs) originating from solvent-based industrial processes. The varied composition tends to influence each VOC's catalytic behavior in the reaction mixture. We investigated the catalytic destruction of multi-component VOCs including dichloromethane (DCM) and ethyl acetate (EA), as representatives from pharmaceutical waste gases, over co-supported HPO-RuO/CeO catalyst.

Soluble carbon source recovery using preconditioning coagulants for applicable short-term fermentation of waste activated sludge in WWTPs.

A huge production of waste activated sludge (WAS) has been a burden for wastewater treatment plants (WWTPs) with high disposal cost and little benefit back to wastewater purification. The short-chain fatty acids (SCFAs) produced by a short-term acidogenic fermentation of WAS before methane production have been proven to be a high-quality carbon source available for microbial denitrification process. The dual purpose of full recovery of fermentation liquid products and facilitating disposal of residual solid waste necessitate an efficient solid-liquid separation process of short-term fermentation liquid.

Activated phosphoinositide 3-kinase δ syndrome caused by PIK3CD mutations: expanding the phenotype.

Background: Germline heterozygous gain-of-function (GOF) mutations in the PIK3CD gene lead to a rare primary immunodeficiency disease known as activated phosphoinositide 3-kinase (PI3K) δ syndrome type 1(APDS1). Affected patients present a spectrum of clinical manifestations, particularly recurrent respiratory infections and lymphoproliferation, increased levels of serum immunoglobulin (Ig) M, Epstein-Barr virus (EBV) and cytomegalovirus (CMV) viremia. Due to highly heterogeneous phenotypes of APDS1, it is very likely that suspected cases may be misdiagnosed.

DeepMesh: Mesh-Based Cardiac Motion Tracking Using Deep Learning.

3D motion estimation from cine cardiac magnetic resonance (CMR) images is important for the assessment of cardiac function and the diagnosis of cardiovascular diseases. Current state-of-the art methods focus on estimating dense pixel-/voxel-wise motion fields in image space, which ignores the fact that motion estimation is only relevant and useful within the anatomical objects of interest, e.g.

Surface-Phosphorylated Ceria for Chlorine-Tolerance Catalysis.

An improved fundamental understanding of active site structures can unlock opportunities for catalysis from conceptual design to industrial practice. Herein, we present the computational discovery and experimental demonstration of a highly active surface-phosphorylated ceria catalyst that exhibits robust chlorine tolerance for catalysis. Ab initio molecular dynamics (AIMD) calculations and near-ambient pressure X-ray photoelectron spectroscopy ( NAP-XPS) identified a predominantly HPO active structure on CeO(110) and CeO(111) facets at room temperature.

Palladium Encapsulated by an Oxygen-Saturated TiO Overlayer for Low-Temperature SO -Tolerant Catalysis during CO Oxidation.

The development of oxidation catalysts that are resistant to sulfur poisoning is crucial for extending the lifespan of catalysts in real-working conditions. Herein, we describe the design and synthesis of oxide-metal interaction (OMI) catalyst under oxidative atmospheres. By using organic coated TiO , an oxide/metal inverse catalyst with non-classical oxygen-saturated TiO overlayers were obtained at relatively low temperature.

A bibliometric analysis of metastatic breast cancer: two-decade report (2002-2022).

Background: MBC is a lethal form of breast cancer that arises when cancer cells invade other organs or tissues. The treatment of MBC needs personalized approaches based on the tumor and patient characteristics. The purpose of this paper is to analyze MBC studies from 2002 to 2022 using bibliometrics and to investigate its current situation, main contributors, core journals, highly cited papers, and topic evolution.

Defect Engineering in 0D/2D S-Scheme Heterojunction Photocatalysts for Water Activation: Synergistic Roles of Nickel Doping and Oxygen Vacancy.

Photocatalytic hydrodechlorination (HDC) is a promising method for eliminating chlorinated organic compounds (COCs) from water, but it requires catalysts with excellent water activation ability. Defect engineering is a feasible way to enhance the catalytic performance of photocatalysts by improving light adsorption, charge carrier dynamics, and surface reactions. Herein, a well-designed 0D/2D S-scheme heterojunction with favorable band structures and defective interfaces was constructed via defect tailoring on TiO quantum dots (QDs) and the interface structure.

Icariin Induces Triple-Negative Breast Cancer Cell Apoptosis and Suppresses Invasion by Inhibiting the JNK/c-Jun Signaling Pathway.

Background: Breast cancer is a common cancer worldwide. Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer characterized by a poor prognosis. Icariin (ICA) is a flavonoid glycoside purified from the natural product Epimedium, which is reported to exert an inhibitory effect on a variety of cancers.

A Fluorinated Polyimide Based Nano Silver Paste with High Thermal Resistance and Outstanding Thixotropic Performance.

Because of high conductivity, acceptable cost and good screen-printing process performance, silver pastes have been extensively used for making flexible electronics. However, there are few reported articles focusing on high heat resistance solidified silver pastes and their rheological properties. In this paper, a fluorinated polyamic acids (FPAA) is synthesized by polymerization of the 4,4'-(hexafluoroisopropylidene) diphthalic anhydride and 3,4'-diaminodiphenylether as monomers in the diethylene glycol monobutyl.

Clinical features of CNOT3-associated neurodevelopmental disorder in three Chinese patients.

CNOT3 is the central component of the CCR4-NOT protein complex, which is a global regulator of RNA polymerase II transcription. Loss of function mutations in CNOT3 lead to intellectual developmental disorder with speech delay, autism, and dysmorphic facies (IDDSADF), which is very rare. Herein, we reported two novel heterozygous frameshift mutations (c.

Ultrafine aluminum sulfide nanocrystals anchored on two-dimensional carbon sheets for high-performance lithium-ion batteries.

Aluminum sulfide is a novel light metal sulfide, which possesses multiple advantages for lithium storage, including high theoretical capacity, proper discharge potential and good conductivity. However, much research has not been done in areas related to light metal sulfide materials. Herein, we synthesized AlS/C nanocomposite by a facile one-step ball milling method.

Deep learning-based prediction of effluent quality of a constructed wetland.

Data-driven approaches that make timely predictions about pollutant concentrations in the effluent of constructed wetlands are essential for improving the treatment performance of constructed wetlands. However, the effect of the meteorological condition and flow changes in a real scenario are generally neglected in water quality prediction. To address this problem, in this study, we propose an approach based on multi-source data fusion that considers the following indicators: water quality indicators, water quantity indicators, and meteorological indicators.

A novel CARD11 germline mutation in a Chinese patient of B cell expansion with NF-κB and T cell anergy (BENTA) and literature review.

Germline gain-of-function (GOF) mutations in the gene lead to a rare primary immunodeficiency disease known as B cell expansion with NF-κB and T cell anergy (BENTA). Affected patients present with a polyclonal expansion of B cells, lymphadenopathy, and splenomegaly. Herein, we report a novel germline in-frame three base-pair deletion (c.

Selective Ru Adsorption on SnO/CeO Mixed Oxides for Efficient Destruction of Multicomponent Volatile Organic Compounds: From Laboratory to Practical Possibility.

Ru-based catalysts have been extensively employed for the catalytic destruction of chlorinated volatile organic compounds (VOCs), but their versatility for other routine VOCs' destruction has been less explored. Herein, we show that Ru-decorated SnO/CeO mixed oxides can sustain HO and HCl poisonings and are endowed with extraordinary versatility for a wide range of VOCs' destruction. Selective adsorption of Ru on the cassiterite SnO and CeO nanorods through a Coulomb force can rationally tune the oxidation and dechlorination centers on decorated catalysts, where the epitaxial growth of RuO on top of SnO is endowed with excellent dechlorination ability and that on CeO is functional as an oxidation center; the latter could also activate HO to provide sufficient H protons for HCl formation.

Achieving Partial Nitritation by Treating Sludge With Free Nitrous Acid: The Potential Role of Quorum Sensing.

Partial nitritation is increasingly regarded as a promising biological nitrogen removal process owing to lower energy consumption and better nitrogen removal performance compared to the traditional nitrification process, especially for the treatment of low carbon wastewater. Regulating microbial community structure and function in sewage treatment systems, which are mainly determined by quorum sensing (QS), by free nitrous acid (FNA) to establish a partial nitritation process is an efficient and stable method. Plenty of research papers reported that QS systems ubiquitously existed in ammonia oxidizing bacteria (AOB) and nitrite oxidizing bacteria (NOB), and various novel nitrogen removal processes based on partial nitritation were successfully established using FNA.

The enhancement of ozone-liquid mass transfer performance in a PTFE hollow fiber membrane contactor using ultrasound as a catalyzer.

A comprehensive assessment of a polytetrafluoroethylene (PTFE) hollow fiber membrane contactor and ultrasound for intensifying ozone-liquid mass transfer was conducted simultaneously. The initial part of the study concentrates on the systematic analysis of the previous literature related to the reinforcement on the ozone-liquid mass transfer. In this paper, the introduction of a membrane contactor and ultrasound as a catalyzer that increased the mass transfer coefficient ( ) may be partially attributed to the increase of the net surface area and the decrease of the mass transfer resistance, thus leading to the enhancement of the ozone mass transfer rate and acceleration of the ozone decomposition in solution.

MulViMotion: Shape-Aware 3D Myocardial Motion Tracking From Multi-View Cardiac MRI.

Recovering the 3D motion of the heart from cine cardiac magnetic resonance (CMR) imaging enables the assessment of regional myocardial function and is important for understanding and analyzing cardiovascular disease. However, 3D cardiac motion estimation is challenging because the acquired cine CMR images are usually 2D slices which limit the accurate estimation of through-plane motion. To address this problem, we propose a novel multi-view motion estimation network (MulViMotion), which integrates 2D cine CMR images acquired in short-axis and long-axis planes to learn a consistent 3D motion field of the heart.

Video Summarization Through Reinforcement Learning With a 3D Spatio-Temporal U-Net.

Intelligent video summarization algorithms allow to quickly convey the most relevant information in videos through the identification of the most essential and explanatory content while removing redundant video frames. In this paper, we introduce the 3DST-UNet-RL framework for video summarization. A 3D spatio-temporal U-Net is used to efficiently encode spatio-temporal information of the input videos for downstream reinforcement learning (RL).

Exploring a new paradigm for the fetal anomaly ultrasound scan: Artificial intelligence in real time.

Objective: Advances in artificial intelligence (AI) have demonstrated potential to improve medical diagnosis. We piloted the end-to-end automation of the mid-trimester screening ultrasound scan using AI-enabled tools.

Methods: A prospective method comparison study was conducted.

Identification and Characterization of a Germline Mutation in CARD11 From a Chinese Case of B Cell Expansion With NF-κB and T Cell Anergy.

B cell expansion with NF-κB and T cell anergy (BENTA) is a rare primary immunodeficiency disorder caused by gain-of-function (GOF) mutations in the gene. Affected patients present with persistent B cell lymphocytosis in early childhood paired with lymphadenopathy and splenomegaly. Until now only six activating mutations from 14 patients have been reported in .

Idiopathic Granulomatous Mastitis: Etiology, Clinical Manifestation, Diagnosis and Treatment.

Idiopathic granulomatous mastitis (IGM) is a rare form of chronic inflammatory breast disease. Although it is a benign breast lesion, it may be sometimes difficult to distinguish from breast cancer. The cause of IGM is unknown, but may be associated with autoimmunity, abnormal hormone levels and infection.