Publications by authors named "Qingge Zhang"
Article Synopsis
- * Analyzing data from 8,709 participants over five years, researchers found that increases in cognitive scores were tied to specific daily training durations.
- * Optimal CCT doses were determined to be 25-30 minutes per day for participants under 60 and 50-55 minutes for those 60 and older, indicating that the effectiveness of training varies with age.
Article Synopsis
- Patients with clinically significant portal hypertension (CSPH) should be treated with non-selective beta-blockers like carvedilol to prevent liver decompensation, especially using liver stiffness (LS) measurements as a less invasive alternative to hepatic venous pressure gradient (HVPG) measurements.
- A study is planned to determine if patients with compensated cirrhosis and LS≥25 kPa can benefit from carvedilol, focusing on a randomized, double-blind, placebo-controlled trial involving 446 adults.
- The primary outcome will be the incidence of decompensation events and liver-related deaths over three years, while secondary outcomes will include various complications of portal hypertension such as
Background: Age-related cognitive decline is a chronic, progressive process that requires active clinical management as cognitive status changes. Computerized cognitive training (CCT) provides cognitive exercises targeting specific cognitive domains delivered by computer or tablet. Meanwhile, CCT can be used to regularly monitor the cognitive status of patients, but it is not clear whether CCT can reliably assess cognitive ability or be used to diagnose different stages of cognitive impairment.
View Article and Find Full Text PDFBackground: Only a small proportion of patients with compensated advanced chronic liver disease (cACLD) had varices needing treatment (VNT) after recommended esophagogastroduodenoscopy (EGD) screening. We aimed to create a non-invasive nomogram based on routine tests to detect VNT in cACLD patients.
Methods: The training cohort included 162 cACLD patients undergoing EGD in a university hospital, between January 2014 and September 2019.
Objectives: A liver stiffness × spleen size/platelet count score (LSPS) model which can rule out high-risk varices and identify high likelihood of clinically significant portal hypertension in patients with compensated cirrhosis has been endorsed by American Association for the Study of Liver Diseases in the 2016 practice guidance on portal hypertension bleeding. This study aims to evaluate the accuracy of LSPS model assessed by ultrasound in well characterized patients with compensated advanced chronic liver disease.
Methods: Eligible patients with compensated advanced chronic liver disease were retrospectively enrolled between January 2017 and March 2018, who had undergone routine clinical and laboratory tests, liver stiffness measurement, ultrasound examination, and computed tomography scanning.
Clinically significant portal hypertension (CSPH) is associated with an incremental risk of esophageal varices and overt clinical decompensations. However, hepatic venous pressure gradient (HVPG) measurement, the gold standard for defining CSPH (HVPG≥10 mm Hg) is invasive and therefore not suitable for routine clinical practice. This study aims to develop and validate a radiomics-based model as a noninvasive method for accurate detection of CSPH in cirrhosis.
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