Association between Cervical Lymph Node Metastasis and the Incidence of Radiation-Induced Hypothyroidism in Nasopharyngeal Carcinoma.

Background: It is controversial and unclear how -stage would increase the risk of incidence of hypothyroidism (HT) for patients with nasopharyngeal carcinoma (NPC) after radiotherapy. Our study aimed to explore the correlation between cervical lymph node metastasis and the incidence of HT in NPC.

Materials And Methods: A total of 206 patients with NPC treated at the Cancer Hospital of University of Chinese Academy of Sciences, and their clinical information were retrospectively collected.

Clarifying the pharmacological mechanisms of action of Shenfu Decoction on cardiovascular diseases using a network pharmacology approach.

Since the molecular mechanisms underlying in the pathogenesis of cardiovascular diseases (CVD) are extremely complex and have not yet been elucidated in detail, CVD remain the leading cause of death worldwide. Traditional Chinese medicine involves the treatment of disease from an overall perspective, and its therapeutic effects on CVD have been demonstrated. However, the mechanisms contributing to the multiscale treatment of cardiovascular diseases at the systematic level remain unclear.

Use of an electrophysiological technique for stepwise detection of trace agonist constituents of Hochuekkito in Xenopus oocytes injected with serotonin 2C receptor mRNA.

An electrophysiological bioassay was used to isolate the active compound from Hochuekkito (HET), which the current authors previously described as having potent agonist action against serotonin 2C receptors (5-HT2CR). Synthetic 5-HT2CR mRNA was injected into Xenopus oocytes to specifically express these receptors. Crude extracts and purified products were subjected to an electrophysiological bioassay using the voltage clamp method.

Effect of biofertilizer and wheat straw biochar application on nitrous oxide emission and ammonia volatilization from paddy soil.

Biofertilizer can improve soil quality, especially the microbiome composition, which potentially affect soil nitrogen (N) cycling. However, little is known about the responses of nitrous oxide (NO) emission and ammonia (NH) volatilization from biochar-amended paddy soil to the biofertilizer application. Therefore, we conducted a soil column experiment using four 240 kg N ha (equivalent to 1.

Guanxin V for coronary artery disease: A retrospective study.

Background: Guanxin V (GXV), a traditional herbal mixture, has been widely used in clinical practice for the treatment of coronary artery disease (CAD). This retrospective study was designed to assess the safety and effectiveness of GXV for CAD.

Methods: In our study, December 2006 to January 2009, 101 patients with CAD from Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine were enrolled, of whom 52 patients received GXV plus guideline-recommended medical therapy (GMT) (GXV group), 49 patients received GMT alone (GMT group).

Mechanical Performances of Al-Si-Mg Alloy with Dilute Sc and Sr Elements.

Due to its excellent comprehensive performances, Al-Si-Mg alloy i widely used in automotive, transportation and other fields. In this work, tensile performances and fracture behavior of Al-Si-Mg alloy modified by dilute Sc and Sr elements (Al-7.12Si-0.

Structural Comparison of Gene Relevance Networks for Breast Cancer Tissues in Different Grades.

Background: The breast is an important biological system of human with two distinct states, i.e. normal and tumoral.