Effects of recombinant human growth hormone injection combined with Anastrozole on height and growth rate of adolescent idiopathic short stature and evaluation of adverse reactions.

Recombinant human growth hormone (rhGH) injections combined with Anastrozole are increasingly used to treat adolescent idiopathic short stature (ISS), warranting further research. This study evaluated their effects on height, growth rate and adverse reactions in 72 adolescents with ISS treated at our hospital from December 2021 to December 2022. Patients were divided into a control group (rhGH alone) and a study group (rhGH + Anastrozole).

Cryptococcus neoformans osteomyelitis of the radius treatment with antifungal calcium sulphate: A case report and literature review.

Background: is an opportunistic fungal pathogen widely distributed in nature, commonly found in soil and bird droppings such as pigeons. Cryptococcal osteomyelitis is usually found in immunocompromised patients, in an unusual condition Cryptococcus invades the bone. It usually occurs as a part of disseminated infection and is rarely isolated, and isolated cryptococcal osteomyelitis of the radius is rarer.

Processing of Noni Liquor based on response surface methodology.

Noni ( L.) is widely used as a health food and medicine because it is rich in polysaccharides, polyphenols, and flavonoids; it is precisely because noni is rich in these substances that people usually like to soak it in liquor to drink. This study sought to maximize the main active constituents (polysaccharides, polyphenols, and flavonoid s) dissolved in liquor and spirits soaked with noni fruit, using ethanol as the solvent to optimize the extraction conditions using response surface methodology.

Polysaccharides and polyphenol in dried fruit tea after different processing conditions: Optimization analysis using response surface methodology.

The increasing popularity of has many medical and health benefits because of its rich polysaccharides (PSC) and polyphenols (PPN). It has become popular to brew the dry fruit slice as tea in some regions of China. In this study, optimize the extraction parameters of tea polysaccharides and polyphenols using response surface methodology.

The function of long noncoding RNA HOTAIRM1 in the progression of prostate cancer cells.

Emerging evidence is indicating the importance of hundreds of long noncoding RNAs (lncRNAs) in the occurrence and progression of different malignancies such as prostate cancer (PCa). This study investigated the possible role of HOX transcript antisense intergenic RNA myeloid-specific 1 (HOTAIRM1) in the progression of tumorigenesis of PC3 as PCa cell line. RT-qPCR was used to measure HOTAIRM1 expression levels in PC3 and RWPE-1 cell lines.

Lycopene attenuates high glucose-mediated apoptosis in MPC5 podocytes by promoting autophagy via the PI3K/AKT signaling pathway.

Podocyte injury serves an important role during the progression of diabetic nephropathy (DN), and lycopene (Lyc) may display a potential protective effect against DN progression. The effects of Lyc on high glucose (HG)-induced podocyte apoptosis and the underlying mechanisms are not completely understood; therefore, the present study aimed to investigate the effects of Lyc on HG-induced MPC5 podocyte apoptosis and the underlying mechanism. In the present study, MPC5 podocytes were exposed to HG and different doses of Lyc.