Endoscopic cartilage underlay myringoplasty with or without balloon Eustachian tuboplasty for chronic perforation with Eustachian tube dysfunction.

Objective: The objective of this study was to compare the outcomes of endoscopic cartilage underlay myringoplasty(CNM) with or without balloon Eustachian tuboplasty (BET) for the treatment of chronic perforation with Eustachian tube dysfunction (ETD).

Materials And Methods: A total of 50 ears diagnosed with chronic perforation and ETD were randomly divided into receiving alone CNM and CNM + BET. During the 12 months follow-up, the Eustachian tube score (ETS), Eustachian Tube Dysfunction Questionnaire-7 (ETDQ-7), ET inflammation scale, hearing results and graft success rate of the patients were recorded and analyzed.

Carbon reduction attention and financial market stress: A network spillover analysis based on quantile VAR modeling.

As climate change intensifies, attention to the issue of carbon emission reduction has gradually increased. This research constructs a complete set of indicators of carbon reduction attention and financial market stress and applies the quantile VAR method to calculate the volatility spillover between carbon reduction attention and financial market stress. We conclude with the following.

Predictive value of white blood cell to hemoglobin ratio for 30-day mortality in patients with severe intracerebral hemorrhage.

Aim: To explore the predictive value of white blood cell to hemoglobin ratio (WHR) for 30-day mortality in patients with intracerebral hemorrhage (ICH).

Methods: In this cohort study, 2,848 patients with ICH were identified in the Medical Information Mart for Intensive Care (MIMIC)-III and MIMIC-IV. Least absolute shrinkage and selection operator (LASSO) regression screened covariates of 30-day mortality of ICH patients.

Does the short-selling mechanism improve energy security? Evidence from China.

Reducing carbon emissions and improving energy efficiency are essential to respond to global climate change actively. However, improving energy security under resource and environmental constraints is the key for China to achieve high-quality and sustainable development. Thus, using the panel data at the enterprises and regional levels in China from 2013 to 2020, this research develops an energy security index to study the impact of the short-selling mechanism on energy security.

Does energy-consuming right trading have double dividend effect on firm's economic performance and carbon emission?

Whether the market-based environmental regulation policy can achieve a win-win situation of economic growth and carbon emission reduction has always been an academic controversial topic. Taking the pilot policy of energy-consuming right trading (ECRT) of China in 2016 as a quasi-natural experiment, this paper uses the difference-in-differences (DID) method to investigate the policy impact of ECRT on the economic performance and carbon emissions of firms. An economy-environment composite index has been conducted for testing double dividend effect of ECRT.

Two-Compartmental Toxicokinetic Model Predicts Interspecies Sensitivity Variation of Imidacloprid to Aquatic Invertebrates.

Interspecies sensitivity to the same chemical can be several orders of magnitude different. Quantifying toxicologically internal levels and toxicokinetic (TK) parameters is critical in elucidating the interspecies sensitivity. Herein, a two-compartmental TK model was constructed to characterize the uptake, distribution, and elimination kinetics toward interspecies sensitivity to an insecticide, imidacloprid.

Migration Behavior of Inclusions at the Solidification Front in Oxide Metallurgy.

Distribution of inclusions plays an essential role in inducing intracrystalline ferrite, and the migration behavior of inclusions during solidification has a significant influence on their distribution. The solidification process of DH36 (ASTMA36) steel and the migration behavior of inclusions at the solidification front were observed in situ using high-temperature laser confocal microscopy. The annexation, rejection, and drift behavior of inclusions in the solid-liquid two-phase region were analyzed, providing a theoretical basis for regulating the distribution of inclusions.

Effects of recycling hyper-thermal inoculum by repeated batch cultivation into co-composting of sludge and livestock-poultry manure.

The enrichment and adaptation of hyper-thermal compost-derived thermophilic inoculum by repeated batch cultivation (RBC) was conducted by investigating bacterial community. The effects of recycling hyper-thermal inoculum by RBC into co-composting were investigated through evaluating the influences of temperature, pH, moisture, C/N ratio, transformation of nitrogen, composting maturity, humification levels and scanning electron microscopy (SEM). The results showed that RBC enriched the thermophilic bacterial community and nitrogen fixation bacteria of the compost-derived thermophilic inoculum.

Identification of agricultural quarantine materials in passenger's luggage using ion mobility spectroscopy combined with a convolutional neural network.

As economic globalization intensifies, the recent increase in agricultural products and travelers from abroad has led to an increase in the probability of invasive alien species. A major pathway for invasive alien species is agricultural quarantine materials (AQMs) in travelers' baggage. Thus, it is meaningful to develop efficient methods for early detection and prompt action against AQMs.

Trigone ventricular glioblastoma multiforme with trapped temporal horn: A case report.

Background: Intraventricular glioblastoma multiforme (GBM) is extremely rare, especially in the trigone region. This report presents a case of trigone ventricular GBM with trapped temporal horn (TTH).

Case Presentation: A 59-year-old woman was admitted to our department with a 1-month history of rapidly progressive headache, nausea, and weakness in the right lower extremity.

Age-Independent Cardiac Protection by Pharmacological Activation of Beclin-1 During Endotoxemia and Its Association With Energy Metabolic Reprograming in Myocardium-A Targeted Metabolomics Study.

Background We showed that Beclin-1-dependent autophagy protects the heart in young and adult mice that underwent endotoxemia. Herein, we compared the potential therapeutic effects of Beclin-1 activating peptide, TB-peptide, on endotoxemia-induced cardiac outcomes in young adult and aged mice. We further evaluated lipopolysaccharide (lipopolysaccharide)-induced and TB-peptide treatment-mediated alterations in myocardial metabolism.

Evaluation of Parkin in the Regulation of Myocardial Mitochondria-Associated Membranes and Cardiomyopathy During Endotoxemia.

Mitochondrial deficiency is a known pathology in sepsis-induced organ failure. We previously found that mitochondria-associated membranes (MAMs), a subcellular domain supporting mitochondrial status, are impaired in the heart during endotoxemia, suggesting a mechanism of mitochondrial damage occurred in sepsis. Mitophagy pathway E3 ubiquitin ligase Parkin and PTEN-induced kinase 1 (PINK1) controls mitochondrial quality.

Neural Correlates of Physical Activity Moderate the Association Between Problematic Mobile Phone Use and Psychological Symptoms.

Background: Despite the evidence of an association between problematic mobile phone use (PMPU) and psychological symptoms, a few studies explore whether physical activity (PA) could moderate the effect of PMPU on psychological symptoms and its neural substrates. The aim of this study was to examine the association between PMPU and psychological symptoms in late adolescents, along with the potential moderating effect of PA and neural basis by brain gray matter volume (GMV).

Methods: A total of 251 college students reported on their PMPU, PA, and psychological symptoms and subsequently underwent structural magnetic resonance imaging to explore the neural basis of their PA characteristics.

Functional connectivity between the parahippocampal gyrus and the middle temporal gyrus moderates the relationship between problematic mobile phone use and depressive symptoms: Evidence from a longitudinal study.

Background And Aim: Problematic mobile phone use (PMPU) is prevalent and increases the risk for a variety of health problems. However, few studies have explored the neural mechanisms that might render adolescents more or less vulnerable. Here, we aimed to identify whether PMPU is associated with depressive symptoms and whether this relationship is moderated by intrinsic functional connectivity (iFC) which is associated with PMPU.

Simultaneous shortcut nitrification and denitrification in a hybrid membrane aerated biofilms reactor (H-MBfR) for nitrogen removal from low COD/N wastewater.

The residues of nitrogen contaminants due to insufficient organic carbon sources in sewage has always been the main problem faced by wastewater treatment plants in the process of nitrogen removal. In this study, simultaneous shortcut nitrification and denitrification (SND) was achieved in the hybrid membrane aerated biofilm reactor (H-MBfR) for treating low COD/N ratio (∼x223C 4: 1) wastewater. The effects of the aeration pressure and the influent COD/N ratio in H-MBfR were investigated and further optimized by the response surface methodology (RSM).

Inhibition of Jumonji demethylases reprograms severe dilated cardiomyopathy and prolongs survival.

Hypertrophic/dilated cardiomyopathy, often a prequel to heart failure, is accompanied by maladaptive transcriptional changes that contribute to arrythmias and contractile misfunction. Transgenic mice constitutively expressing high levels of calcineurin are known to develop extreme heart hypertrophy, which progresses to dilated cardiomyopathy, and to die several weeks after birth. Here, we characterized aberrant transcriptional and epigenetic pathways in this mouse model and established a pharmacological approach to treat established cardiomyopathy.

[Diagnostic value of multi-slice spiral CT in tympanic wall destruction of middle ear cholesteatoma].

To investigate the correlation between preoperative temporal bone Computed Tomography （CT） findings and intraoperative manifestations in patients with middle ear cholesteatoma. The patients with cholesteatoma undergoing surgery in our hospital from March 2017 to November 2020 were retrospectively analyzed.The temporal bone CT findings of tympanoid wall status before operation and the state of tympanic wall during operation were compared.

Prevalence of Dementia in China in 2015: A Nationwide Community-Based Study.

This study aims to estimate the prevalence of dementia and Alzheimer's disease (AD) and associated risk factors among the general Chinese population. We carried out a nationwide study including 24,117 participants aged 60 years and older in China using a multistage clustered sampling. Dementia and AD were diagnosed according to the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders and the criteria issued by the National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer's Disease and Related Disorders Association.

Matricellular Protein Cilp1 Promotes Myocardial Fibrosis in Response to Myocardial Infarction.

[Figure: see text].

Hepatic FGF21 preserves thermoregulation and cardiovascular function during bacterial inflammation.

Sickness behaviors, including anorexia, are evolutionarily conserved responses to acute infections. Inflammation-induced anorexia causes dramatic metabolic changes, of which components critical to survival are unique depending on the type of inflammation. Glucose supplementation during the anorectic period induced by bacterial inflammation suppresses adaptive fasting metabolic pathways, including fibroblast growth factor 21 (FGF21), and decreases survival.

Prevalence of Parkinson's Disease: A Community-Based Study in China.

Background: China's socioeconomic and population structures have evolved markedly during the past few decades, and consequently, monitoring the prevalence of Parkinson's disease (PD) is crucial.

Objective: This study aimed to investigate the prevalence of PD within Chinese communities, particularly in older people.

Methods: A nationwide study of 24,117 participants, aged 60 years or older, was carried out in 2015 using multistage clustered sampling.

The impact of off-balance-sheet regulations on bank risk-taking: Evidence from China.

The release of new asset management rules has played a positive role in regulating the asset management business of financial institutions, preventing and controlling financial risk. It has also had an important impact on the management of banks' off-balance-sheet (OBS) innovation. This paper uses unbalanced panel data on 75 commercial banks in China from 2007 to 2017 and combines a theoretical and an empirical model to study the development of bank OBS innovation and bank risk taking from the perspective of new asset management regulations.

Effect of Molybdenum on the Impact Toughness of Heat-Affected Zone in High-Strength Low-Alloy Steel.

The microstructure, precipitates, and austenite grain in high-strength low-alloy steel were characterized by optical microscope, transmission electron microscope, and laser scanning confocal microscopy to investigate the effect of Mo on the toughness of steel. The microstructure was refined and the toughness was enhanced after the addition of 0.07% Mo in steel.

Erratum: Dihydroartemisinin inhibits the Raf/ERK/MEK and PI3K/AKT pathways in glioma cells.

[This corrects the article DOI: 10.3892/ol.2015.