Publications by authors named "Qing-yu Wu"

Background: Surgical treatment of functional single ventricle combined with atrioventricular valve regurgitation remains a clinical challenge. The outcomes of atrioventricular valve repair in patients with single ventricle are limited.

Methods: A retrospective study was conducted of all 28 patients with functional single ventricle treated with single-ventricle palliation who underwent atrioventricular valve operation at the First Hospital of Tsinghua University between April 2007 and October 2022.

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Article Synopsis
  • High-power ultrawideband (UWB) radiation systems require multiple modules due to limitations in output from avalanche transistors, which can lead to larger apertures and narrower beams, restricting some applications.
  • A new approach using a power-law time delay distribution method is proposed to optimize the relative excitation times of the modules for better performance, helping prevent undesirable beam splitting during beam broadening.
  • The developed radiation system with 36 modules achieves a peak effective potential of 313.6 kV and a pulse-repetition rate of 20 kHz, while broadening the beam width in the H-plane from 3.9° to 7.9° and allowing for flexible polarization adjustment.
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Background: The treatment of coronary artery disease combined with severe atherosclerotic stenosis proximal to a left anterior descending artery myocardial bridge (LAD-MB) is still controversial. This study aimed to analyze the outcomes of surgical intervention in patients with severe atherosclerotic stenosis proximal to a LAD-MB.

Methods: We retrospectively reviewed all patients with coronary artery disease combined with severe atherosclerotic stenosis proximal to the LAD-MB.

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Background: The surgical strategy among patients with malignancy and coronary artery disease (CAD) remains controversial. In this study, we present the experiences of coronary artery bypass grafting (CABG) in patients with malignancy and analyzed the treatment outcomes.

Methods: From January 2011 to October 2021, eight patients combined with coronary artery disease and malignancy, six of them with three-vessel disease and two with anterior descending branch lesions on coronary angiography.

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Ecological ditches and bioretention ponds have received widespread attention and application due to their runoff pollution control capabilities and ecological benefits. However, a single ecological ditch or bioretention pond often has problems, such as unstable nitrogen and phosphorus removal and substrate clogging in rural runoff pollution control. Thus, we connected the two facilities in a series to construct a combined system, using the ecological ditch to pretreat, therefore reducing the pollution load of the bioretention pond and mitigating substrate clogging.

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Objective: To analyze the incidence and associated factors of hypothyroidism after radioiodine treatment for hyperthyroidism during a 13-year follow-up period.

Subjects And Methods: This was a retrospective study of consecutive patients with hyperthyroidism who were treated using a single dose of radioactive iodine (RAI) with a calculated dose regimen from 07/2005 to 12/2012. Univariate and multivariate Cox regression models were used to examine the factors that are associated with the occurrence of hypothyroidism after RAI therapy.

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Objective: To investigate the value of  Ga-PSMA-11 positron emission tomography/computerized tomography (PET/CT) in evaluating lacrimal and salivary glands function.

Methods: Ten patients with pSS and 18 healthy volunteers were recruited in this study. All participants underwent  Ga-PSMA-11 PET/CT, and the patients with pSS performed salivary gland scintigraphy the next day.

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Background: Aortic valve replacement (AVR) for chronic aortic regurgitation (AR) with a severe dilated left ventricle and dysfunction leads to left ventricle remodeling. But there are rarely reports on the left ventricle reverse remodeling (LVRR) after AVR. This study aimed to investigate the LVRR and outcomes in chronic AR patients with severe dilated left ventricle and dysfunction after AVR.

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Background: Ebstein's anomaly (EA) has various spectrums in clinical and anatomic features. This study aimed to report the experience of two-dimensional intraoperative transesophageal echocardiography (2D-ITEE) during the EA surgery and to analyze the characteristics of the tricuspid valve (TV) by comparing the data from 2D-ITEE with the results from the surgery.

Methods: 2D-ITEE data of 164 patients with EA who were operated in the First Hospital of Tsinghua University between July 2004 and April 2014 were retrospectively analyzed in this study.

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Background: Double outlet right ventricle (DORV) is a group of complex congenital heart abnormalities. Preoperative pulmonary hypertension (PH) is considered an important risk factor for early death during the surgical treatment of DORV. The aim of this study was to report our experience on surgical treatment of DORV complicated by PH.

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Objective: To investigate the feasibility, advantages and efficacy of implantation of left atrial and ventricular epicardial dual chamber pacemaker to treat pediatric complete atrioventricular block.

Method: Eleven children with median age 4.0 years (0.

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Von Hippel-Lindau (VHL) is a tumor suppressor that negatively regulates the production of angiogenic factors. Mutations in the VHL gene cause VHL syndrome, which is characterized by highly vascularized tumors. Here we report a c.

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Objective: To summarize the experience in anesthetic management for correction of Ebstein's anomaly.

Methods: A total of 79 patients with Ebstein's anomaly who underwent surgical repair in our hospital during the time from March 2004 to September 2010 were retrospectively summarized for their anesthetic management. Anesthesia was done for the patients undergoing correction of Ebstein's anomaly.

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Background: Tetralogy of Fallot (TOF) is the most common malformation of children with an incidence of approximately 10% of congenital heart disease patients. There can be a wide spectrum to the severity of the anatomic defects, which include ventricular septal defect, aortic override, right ventricular outflow tract obstruction, and right ventricular hypertrophy. We examined the relationship between right ventricular hypertrophy in patients with TOF and the gene expression of factors in the mitogen-activated protein kinase (MAPK) signal pathway.

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This case report we presented is that the anomalous left main coronary artery (LMCA) originates from the proximal segment of right coronary artery. In order to confirm the origin and course of the anomalous LMCA, a multi-slice computed tomography (MSCT) of the heart was performed on a 64-slice machine (Philips 64 Slice, Philips, USA) after 6 months of coronary angiography operation. The results showed that the anomalous LMCA originates from the proximal segment of right coronary artery, lies posteriorly to the aorta before taking acute sharply to go between the aorta and left atrium.

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Background: Pulmonary artery sarcoma originating from the pulmonary artery is a rare disease and its prognosis is extremely poor. Most patients are initially thought to have pulmonary embolism.

Methods: Five patients (3 males and 2 females, mean age was (42.

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Objective: To investigate the effect of different methods of anticoagulation after mechanical valve replacement.

Methods: Totally 172 cases of mechanical valve replacement performed from October 2005 to June 2008 were divided into two groups and then analyzed retrospectively. Patients on warfarin and heparin were classified as the heparin group while those on warfarin alone were classified as the warfarin group.

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Article Synopsis
  • The study examined the outcomes of a one-stage surgical repair for congenital aortic arch disease in 25 patients aged 26 days to 6.5 years, with various associated cardiac defects from 1993 to 2009.
  • Surgical techniques included the excision of specific tissues and reconstruction using the patient's own pulmonary artery wall, leading to a successful recovery for 24 patients, with no significant postoperative complications.
  • Results indicated that using autologous tissue for repair not only supports growth but also shows promising long-term outcomes, with no signs of restenosis in follow-up examinations.
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  • Cyanobacteria have diverse ecological habitats and genome sizes, and this study focuses on metacaspases (MCAs), which are important for programmed cell death, to better understand their distribution and evolution across different cyanobacterial species.
  • A total of 58 potential MCAs were found, mainly in filamentous cyanobacteria, with specific mutations present in some species; two main families of MCAs (alpha and beta) were identified based on their structure, with various additional domains implicated in signal transduction.
  • The study suggests that the presence of MCA genes is linked to the organisms' genome size and environment, highlighting the distinct evolutionary paths of the alpha and beta MCA families, and laying the groundwork for future research on their
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