Publications by authors named "Qing-yi Mai"
[Effects of cisplatin on telomerase activity of human choroidal melanoma cells].
Zhonghua Yan Ke Za Zhi
August 2008
Article Synopsis
- The study investigates how cis-dichlorodiamine platinum (CDDP) affects telomerase activity and induces toxicity in human choroidal melanoma cells.
- CDDP was applied at various concentrations and durations, revealing that it inhibits telomerase activity while also reducing cell viability in a dose- and time-dependent manner.
- There is a significant negative correlation between telomerase inhibition and cell toxicity, indicating that while telomerase activity decreases with CDDP exposure, cell death occurs later.