Publications by authors named "Qing-shui Ying"
Article Synopsis
- This study explores a new surgical method for treating irreducible atlantoaxial dislocation (IAAD) and basilar invagination (BI) using a transoral approach, focusing on osteotomy and plate fixation to correct bony deformities.
- The researchers conducted the procedure on 213 patients between March 2015 and December 2019, addressing various bony factors that hindered reduction and causing symptoms like neck pain, headaches, and mobility issues.
- Post-surgery results showed significant improvement in key measurements, with notable reductions in average anteroposterior diameter and cervical angles, alongside enhanced clinical symptoms and overall patient recovery as indicated by improved JOA scores.
Objective: Spinal fusion is one of the most common surgical interventions for spine reconstruction. Despite the efforts to promote osteogenesis after spinal fusion, osteogenesis after spinal fusion remains a clinical challenge and new methods are still needed. The bone morphogenetic protein-2 (BMP-2) is a widely reported factor that can facilitate the osteogenesis in spinal fusion.
View Article and Find Full Text PDFIn the present study, the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) delivered by chitosan (CS) microspheres on ectopic osteogenesis was investigated in a rat model. rhBMP-2-loaded CS microspheres and blank CS microspheres were prepared. A total of 24 male Sprague Dawley rats were divided into 4 groups with 6 rats in each group: The CS/rhBMP-2 group, the rhBMP-2 group, in which rhBMP-2 was directly implanted (rhBMP-2 dose in either group, 1 mg), the CS blank group and the control group.
View Article and Find Full Text PDFBone morphogenetic protein-2 (BMP-2) serves an important role in the development of bone and cartilage. However, administration of BMP-2 protein alone by intravenous delivery is not very effective. Sustained delivery of stabilized BMP-2 by carriers has been proven necessary to improve the osteogenesis effect of BMP-2.
View Article and Find Full Text PDFObjective: To discuss the reasons for the operation performed on 13 patients with upper cervical disease and to explore the management and prevention of upper cervical disease.
Methods: Thirteen patients with upper cervical disease were retrospectively reviewed. The reason for of reoperations on these patients were analyzed.