Publications by authors named "Qing-hu Li"
Background: The management of vascular graft infections continues to be a significant challenge in a clinical situation. The aim of this report is to illustrate the novel vacuum sealing drainage (VSD) technique and rectus femoris muscle flap transposition for vascular graft infections, and to evaluate the prospective of future testing of this surgical procedure.
Case Summary: We report the case of a 32-year-old male patient, who presented a severe infected groin wound with biological vascular graft infection resulting in extensive graft exposure.
Objective: To investigate the clinical efficacy and outcomes of the coracoid osteotomy with or without Bristow-Latarjet procedures in the treatment of chronic anterior shoulder dislocation (CASD).
Methods: Between January 2013 and January 2019, 20 shoulders of 18 patients who were diagnosed with chronic anterior dislocation and underwent open reduction in our trauma center were retrospectively studied. Open coracoid osteotomy with Bristow-Latarjet procedures were performed on 16 shoulders and open coracoid osteotomy without Bristow-Latarjet procedures were performed on four shoulders.
Article Synopsis
- Hoffa fractures are rare coronal fractures of the distal femur that can be misdiagnosed and are typically treated with surgery, focusing on open reduction and internal fixation.
- This study presents two cases of nonunion in a 56-year-old female and a 64-year-old male, both of whom underwent successful surgical intervention using autologous bone grafts and specific fixation devices, resolving their symptoms without complications.
- The findings emphasize the effective use of bone grafts and specific hardware for treating nonunion in Hoffa fractures, along with the necessity of careful follow-up to monitor for any potential complications.
In this study, we developed a novel poly (lactic-co-glycolic acid)-dextran (PLD)-based nanodelivery system to enhance the anticancer potential of cisplatin (CDDP) in osteosarcoma cells. A nanosized CDDP-loaded PLGA-DX nanoparticle (PLD/CDDP) controlled the release rate of CDDP up to 48 h. In vitro cytotoxicity assay showed a superior anticancer effect for PLD/CDDP and with an appreciable cellular uptake via endocytosis-mediated pathways.
View Article and Find Full Text PDFThe aim of the present investigation was to formulate a docetaxel (DTX) and gemcitabine (GEM) co-loaded PEGylated liposome (DTX/GEM-L) to increase the therapeutic efficacy in osteosarcoma (OS). 2-Hydroxypropyl-γ-cyclodextrin/DTX inclusion complex was made to increase DTX aqueous solubility. DTX/GEM-L was characterized for morphological shape and size parameters.
View Article and Find Full Text PDF