Publications by authors named "Qing-guo Lai"

Objective: To investigate the clinical immediate load at an angle after immediate placement of the implant.

Methods: Select 4 adult dogs; through establishing the angle loading animal experiment model, perform lateral loading on 32 implants respectively at vertical and 0°, 10°, and 20°, with which as a basis for grouping, determine the osseointegration index and new bone growth rate; and observe the peri-implant bone remodeling conditions.

Results: The 20° group is found with the most obvious bone absorption, and compared with other groups, its osseointegration index and new bone growth rate are statistically significant (P < 0.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigated how stress is distributed in bone around dental implants when subjected to different angles of loading (0, 5, 10, and 20 degrees).
  • Using ANSYS software, researchers assessed the stress at the implant-bone interface with a focus on the implant neck, middle, and apex areas under a load of 200 N.
  • Results showed that stress concentration increased significantly at the neck of the implant with a 20-degree load, while changes in stress at lower angles (0, 5, and 10 degrees) were less pronounced, suggesting that angles greater than 20 degrees warrant further attention for implant stability.
View Article and Find Full Text PDF

This study was designed to investigate the effects of local delivery of adipose-derived stem cells (ADSCs) transfected with transcription factor osterix (OSX) on bone formation during distraction osteogenesis. New Zealand white rabbits (n=54) were randomly divided into three groups (18 rabbits per group). A directed cloning technique was used for the construction of recombinant plasmid pEGFP-OSX, where EGFP is the enhanced green fluorescence protein.

View Article and Find Full Text PDF

This study was designed to investigate the effects of local delivery of bone marrow mesenchymal stem cells (BMMSCs) with or without osterix (OSX) gene transfected on bone regeneration in the distracted zone using a rabbit model of mandibular lengthening. Fifty-four New Zealand white rabbits underwent osteodistraction of the left mandible and were then randomly divided into group A, group B, and group C (n = 18 for each group). At the end of distraction BMMSCs transfected with OSX, autologous BMMSCs and physiological saline were injected into the distraction gaps in groups A, B, and C, respectively.

View Article and Find Full Text PDF

Purpose: To investigate the efficacy of NG-methyl-L-arginine(L-NMMA) for treatment of indirect temporomandibular joint trauma in goats.

Methods: Trauma to TMJ in 9 goats were exerted under an impact to the right and left mandibular angle with self-made device, L-NMMA (0.5 mL) were injected into the right TMJs after 3 hours, 7 days, 14 days, 21 days; the left TMJs were injected with normal saline and used as a control.

View Article and Find Full Text PDF

A high-flow maxillary arteriovenous malformation fed by multiple arteries, including bilateral internal maxillary arteries and ophthalmic artery, is reported. A combination of polyvinyl alcohol particles and N-butyl-cyanoacrylate mixed with lipiodol was progressively deposited within the distal vascular bed by transarterial superselective embolization of the branches of bilateral internal maxillary arteries, resulting in complete anatomic and clinical cure. The authors feel that this approach is more secure and effective compared with transfemoral venous embolization and direct transosseous puncture.

View Article and Find Full Text PDF

Objective: To study the association of transforming growth factor-alpha (TGF-alpha gene polymorphism and environment factors with nonsyndromic cleft lip with or without cleft palate (NSCLP) in Han nationality.

Methods: Data related to infection, drug intake and folic acid supplement during pregnancy were gained through investigation of mothers. Polymerase chain reaction combined with restrict enzyme digestion was used to detect the target gene variation in 199 patients with NSCL/P and 203 healthy controls.

View Article and Find Full Text PDF

Purpose: To observe the clinical effects of low intensity ultrasound in extraction of totally impacted third molars.

Methods: 40 patients with totally impacted third molars on both sides of the mandible verified by X-ray were selected. After extraction of the teeth, the socket on one side was treated with low intensity ultrasound while the other side underwent no treatment.

View Article and Find Full Text PDF

Objective: To study the association of TGF-alpha gene polymorphism and non-syndromic cleft lip with cleft palate in Shandong province.

Methods: Polymerase chain reaction combined with restrict enzyme digestion was used to detect the target gene variation in 98 patients with non-syndromic cleft lip with cleft palate and 101 healthy controls.

Results: The C2 allele frequency in patients with non-syndromic cleft lip with cleft palate was significantly higher than that in healthy controls.

View Article and Find Full Text PDF

Purpose: The aim of this study was to investigate the histopathological changes of human temporomandibular joint osteoarthrosis following intra-articular injection of triamcinolone acetonide, and compare the results to these of control group.

Methods: The upper compartments of both joints of 10 goats were injected with 0.8 ml collagenase I to induce osteoarthrosis.

View Article and Find Full Text PDF

Purpose: To analyse the results of using Bioglass to repair alveolar cleft.

Methods: Thirty-nine cases with alveolar cleft were divided into two groups. In group A, autogenous iliac cancellous bone were transplanted into the cleft to repair alveolar defect in 25 cases, while artificial bone-Bioglass was used in group B of 14 cases.

View Article and Find Full Text PDF

Objective: To study the role of Ca2+ overload and energy metabolism in mitochondria in masticatory muscle dysfunctional induced by occlusal trauma.

Methods: Mitochondrial Ca2+ contents were measured with atomic emission spectrophotometer. Mitochondrial ATP and ADP contents were measured with high performance liquid chromatography.

View Article and Find Full Text PDF