[Characteristics of Ozone Concentration in Shanghai and Its Associated Atmospheric Circulation Background During Summer Half-years from 2006 to 2021].

It is of great importance to scientifically evaluate the impact of weather and climate conditions on the occurrence of O pollution in order to improve the accuracy of O pollution forecasts， as well as to reasonably control and reduce the adverse effects of O pollution. The characteristics of O concentration and climate background were analyzed based on daily O concentration data， meteorological factors， and NCEP/NCER reanalysis data from 2006 to 2021 in Shanghai. In addition， the differences in atmospheric circulation situations during years with anomalous O concentrations were compared and diagnosed from the perspective of climatology.

CircRNA_102179 promotes the proliferation, migration and invasion in non-small cell lung cancer cells by regulating miR-330-5p/HMGB3 axis.

Non-small cell lung cancer (NSCLC) accounting for 85 % of all lung cancer was one of the main causes of death worldwide. In this study, we investigated the role of circRNA_102179 in NSCLC development. The levels of circRNA_102179 in NSCLC tissues and cell lines were determined by quantitative real-time PCR assay (qRT-PCR).

Autocrine Complement Inhibits IL10-Dependent T-cell-Mediated Antitumor Immunity to Promote Tumor Progression.

Unlabelled: In contrast to its inhibitory effects on many cells, IL10 activates CD8(+) tumor-infiltrating lymphocytes (TIL) and enhances their antitumor activity. However, CD8(+) TILs do not routinely express IL10, as autocrine complement C3 inhibits IL10 production through complement receptors C3aR and C5aR. CD8(+) TILs from C3-deficient mice, however, express IL10 and exhibit enhanced effector function.

Evaluation of the 7th edition of the TNM classification in patients with resected esophageal squamous cell carcinoma.

Aim: To evaluate the prognostic factors and tumor stages of the 7(th) edition TNM classification for esophageal cancer.

Methods: In total, 1033 patients with esophageal squamous cell carcinoma (ESCC) who underwent surgical resection with or without (neo)adjuvant therapy between January 2003 and June 2012 at the Thoracic Surgery Department II of the Beijing Cancer Hospital, Beijing, China were included in this study. The following eligibility criteria were applied: (1) squamous cell carcinoma of the esophagus or gastroesophageal junction identified by histopathological examination; (2) treatment with esophagectomy plus lymphadenectomy with curative intent; and (3) complete pathologic reports and follow-up data.

[Effect of PC cell-derived growth factor RNA interference on biological behavior of esophageal squamous carcinoma cells].

Objective: To investigate the effect of PC cell-derived growth factor (PCDGF) RNA interference on esophageal squamous carcinoma cells Eca-109 in vitro.

Methods: The PCDGF-shRNA expression vector was transfected into the Eca-109 cells by liposome. After transfection, the mRNA and protein expressions of PCDGF were detected by RT-PCR and Western-blot respectively.

[Perioperative nutrition support for esophageal cancer complicated with diabetes mellitus].

Objective: To compare the efficacy between perioperative enteral and parenteral nutrition support for esophageal cancer patients complicated with diabetes mellitus.

Methods: Thirty esophageal cancer patients complicated with diabetes mellitus between September and November 2012 were prospectively enrolled in this trial. According to random number table, 30 cases were randomly divided into enteral group (n=15) and parenteral group (n=15).

[Diagnostic value of enhanced computed tomography plus vascular endothelial growth factor C expression in hilar and mediastinal lymph node metastasis of non-small cell lung cancer].

Objective: To explore the diagnostic value of preoperative enhanced computed tomography (CT) plus vascular endothelial growth factor C (VEGF-C) expression in hilar and mediastinal lymph nodes metastasis of non-small cell lung cancer.

Methods: A total of 87 patients with non-small cell lung cancer (NSCLC) received preoperative chest enhanced CT scans and underwent standard radical operation and systematic lymph node dissection. Pathologic examination was selected as the gold standard to determine lymph node metastasis.

[Clinical application of minimally invasive esophagectomy for esophageal carcinoma].

Objective: To investigate the feasibility and safety of minimally invasive esophagectomy (MIE) for esophageal carcinoma.

Methods: Clinical data of 298 esophageal carcinoma cases who were treated by MIE in the Fujian Provincial Cancer Hospital from June 2008 to April 2012 were retrospectively reviewed.

Results: All the patients underwent MIE successfully except one conversion to open surgery.

[Diagnostic accuracy research of needle puncture biopsy during operation for pulmonary single nodules].

Objective: To investigate the diagnostic accuracy of needle puncture biopsy and pathological examination of frozen during operation for pulmonary nodules, and whether this diagnostic method can replace tumor resection examination.

Methods: Totally 50 patients (28 males and 22 females, average age was 59 years) who had the single nodule after imaging examination without any pathological diagnostic from January to October 2010 were selected in this research work. During open operation or video assisted thoracic surgery, needle (14 G model) was used to puncture biopsy for pathological examination of frozen.

Omentoplasty in preventing anastomotic leakage of oesophagogastrostomy following radical oesophagectomy with three-field lymphadenectomy.

Objectives: Anastomotic leakage is a major cause of mortality in oesophageal surgery. Whether omentoplasty after oesophagogastrostomy could reduce anastomotic leakage is still controversial. The aim of this study is to investigate the function of omentoplasty to reinforce cervical oesophagogastrostomy after radical oesophagectomy with three-field lymphadenectomy.

[Study of different enteral nutrition formulation treatment after esophagectomy].

Objective: To compare the efficiency of different early enteral nutrition (EN) with Ensure, Nutrison, and Peptison in postoperative patients with esophageal carcinoma.

Methods: A total of 45 postoperative patients with esophageal carcinoma were randomly divided into three groups using random digit table: Ensure group (n=15), Nutrition group (n=15), and Peptison group (n=15). Enteral nutrition was given using nasogastric tube from the 2nd postoperative day for 8 days.

Recombinant immunotoxin anti-c-Met/PE38KDEL inhibits proliferation and promotes apoptosis of gastric cancer cells.

Background: Our study aims to evaluate the anti-growth effects of recombinant immunotoxin (IT) anti-c-Met/PE38KDEL on gastric cancer cells, and its mechnisms.

Methods: Gastric cancer cells were treated with increasing doses of IT and c-Met protein was quantified by Western blotting. Cell proliferation was determined by Cell Counting Kit-8 assay (CCK).

[Role of pulmonary segmental and sub-segmental lymph nodes in pathological staging of lung cancer].

Objective: To investigate the metastatic rate of segmental and/or sub-segmental lymph nodes and their roles in pathological staging after a major pulmonary resection.

Methods: This prospective study recruited 90 cases of pulmonary resection performed at our department from February 2007 to February 2008. Hilar lymph nodes (No.

[Analysis of serum protein fingerprints on non-small cell lung cancer lymphatic metastasis].

Objective: To establish a classification model and serum proteomic patterns in non-small cell lung cancer (NSCLC) patients with lymph node metastasis by surface enhanced laser desorption/ionization time of flight mass spectrometry (SELDI-TOF-MS).

Methods: The relative contents of serum proteins of 84 NSCLC patients with different N stages (35 N0 cases, 19 N1 and 30 N2 respectively) were detected by CM10 chip and SELDI-TOF-MS; two decision trees were generated to distinguish lymph nodes metastasis (N0 versus N1 + N2) and mediastinal lymph nodes metastasis (N0 + N1 versus N2) respectively.

Results: The model in which 50 patients were randomly chosen differentiated patients with lymph nodes metastasis from N0 patients with a sensitivity of 96.

[Application of the 2007 lung cancer staging system by International Association for the Study of Lung Cancer].

Objective: To compare the prognoses of non-small cell lung cancer patients based respectively on the 6th-Edition Staging System for NSCLC (the 6th-Edition Staging System) and the new staging system by the International Association for the Study of Lung Cancer (IASLC) (new staging system).

Methods: Data were collected from 136 operated NSCLC patients from Sep. 2003 through Oct.

[Effect of bilateral intercostal nerve protection on post-thoracotomy pain relief: a prospective single-blinded randomized study].

Objective: To study the efficacy of bilateral intercostal nerve protection on pain relief after thoracotomy.

Methods: Sixty patients in need of thoracotomy were randomized into 3 groups: Group C (control group, undergoing standard posterolateral thoracotomy, n = 18), Group U (unilateral intercostal nerve protection group, undergoing protection of intercostal nerve above the incision based on the standard posterolateral thoracotomy, n = 20), and Group B (bilateral intercostal nerve protection group, undergoing protection of intercostal nerves above and below the incision based on the standard posterolateral thoracotomy, n = 22). Numeric rating scale (NRS) was adopted to document the severity of pain at different time points after surgery.

[Expression of autophagy-related genes Beclin1 and MAPLC3 in non-small cell lung cancer].

Background & Objective: Some studies have indicated that the down-regulation of autophagy-related genes might result in tumorigenesis. This study was to investigate the expression and significance of autophagy-related genes Beclin1 and microtubule-associated protein 1 light chain 3 (MAPLC3) in human non-small cell lung cancer (NSCLC).

Methods: The expression of Beclin1 and MAPLC3 in tumor tissues, adjacent non-cancerous tissues, and normal tissues from 72 specimens of NSCLC were detected by immunofluorescence staining, Western blot, and reverse transcription-polymerase chain reaction (RT-PCR).

[Diagnosis and treatment of intralobar pulmonary sequestration].

Objective: To summarize the diagnosis and surgical treatment of intralobar pulmonary sequestration (PS).

Methods: The clinical data of 7 cases of intralobar PS, 5 males and 2 females, aged 15 - 38, was collected and analyzed. Macroscopic and microscopic pathological findings were recorded.

[Expression of TR4-associated protein in non-small cell lung cancer].

Objective: To investigate the expression and significance of TR4-associated Protein (TRA16) in human non-small cell lung cancer (NSCLC) tissues.

Methods: Immunohistochemistry (IHC) and tissue array were employed to investigate the expression of TRA16 in NSCLC cases of different pathological types, benign lung lesions and normal lung tissues.

Results: The abundant expression of TRA16 was observed in nucleus and/or cytoplasm of NSCLC cells with a positive expression rate of 88.