Microbial cell wall sorption and Fe-Mn binding in rhizosphere contribute to the obstruction of cadmium from soil to rice.

Screening high-tolerant microorganisms to cadmium (Cd) and revealing their bio-obstruction mechanism could be significant for Cd regulation from farmland to the food chain. We examined the tolerance and bio-removal efficiency of Cd ions of two bacterial strains, 23483 and . GY16, and measured the accumulation of Cd ions in rice tissues and its different chemical forms in soil.

Effects of Radiant Floor Heating Integrated with Natural Ventilation on Flow and Dispersion in a Newly Decorated Residence.

To date, few studies have been conducted on the characteristics of flow and dispersion caused by indoor radiant floor heating integrated with natural ventilation. In this study, we employed reduced-scale numerical models validated by wind-tunnel experiments to investigate the influence of radiant floor heating integrated with natural ventilation on airflow, heat transfer, and pollutant dispersion within an isolated building. The Richardson number () was specified to characterize the interaction between the inflow inertia force and the buoyancy force caused by radiant floor heating.

Pharmacological suppression of glycogen synthase kinase-3 reactivates HIV-1 from latency via activating Wnt/β-catenin/TCF1 axis in CD4 T cells.

HIV-1 latency posts a major obstacle for HIV-1 eradication. Currently, no desirable latency reversing agents (LRAs) have been implicated in the "Shock and Kill" strategy to mobilize the latently infected cells to be susceptible for clearance by immune responses. Identification of key cellular pathways that modulate HIV-1 latency helps to develop efficient LRAs.

[Effects of biochar addition on soil moisture infiltration process of the yellow soil in Karst area].

To investigate the effects of biochar addition on soil moisture infiltration characteristics of sloping farmland in Karst area, we used soil column simulation to study the variation characteristics of cumulative infiltration volume, infiltration rate, and wetting peak process under the different biochar addition amount (0, 1% and 2%) and different particle sizes (<0.25, 0.25-1 and >1 mm), and simulated the infiltration process in yellow soil on slope farmland.

Efficacy and safety of the long-acting fusion inhibitor albuvirtide in antiretroviral-experienced adults with human immunodeficiency virus-1: interim analysis of the randomized, controlled, phase 3, non-inferiority TALENT study.

Background: Albuvirtide is a once-weekly injectable human immunodeficiency virus (HIV)-1 fusion inhibitor. We present interim data for a phase 3 trial assessing the safety and efficacy of albuvirtide plus lopinavir-ritonavir in HIV-1-infected adults already treated with antiretroviral drugs.

Methods: We carried out a 48-week, randomized, controlled, open-label non-inferiority trial at 12 sites in China.

Tryptophan Metabolism Activates Aryl Hydrocarbon Receptor-Mediated Pathway To Promote HIV-1 Infection and Reactivation.

Multiple cellular metabolic pathways are altered by HIV-1 infection, with an impact on immune activation, inflammation, and acquisition of non-AIDS comorbid diseases. The dysfunction of tryptophan (Trp) metabolism has been observed clinically in association with accelerated HIV-1 pathogenesis, but the underlying mechanism remains unknown. In this study, we demonstrated that the aryl hydrocarbon receptor (AHR), a ligand-activated transcription factor, is activated by Trp metabolites to promote HIV-1 infection and reactivation.

A systematic review and meta-analysis of naproxen for prevention heterotopic ossification after hip surgery.

Background: The aim of this study was to assess the efficacy of naproxen in preventing heterotopic ossification (HO) after hip surgery (total hip arthroplasty [THA] and hip arthroscopy).

Methods: Using databases (PubMed, EMBASE, and Web of Science), we conducted an electronic, systematic search of randomized controlled trials (RCTs) comparing naproxen versus placebo on HO after hip surgery. The risk ratio (RR) of the dichotomous data, weighted mean difference (WMD) of continuous data, and 95% confidence intervals (CIs) were calculated to assess the effects of naproxen in patients with hip surgery.

[Estimating leaf area index of black locust (Robinia pseudoacacia L.) plantations based on texture parameters of quickbird imagery].

The black locust plantations located in Weibei area were chosen as research objects and the texture parameters of different window sizes from high resolution imagery were measured. Four different techniques, including simple linear regression model, quadratic regression model, power model and exponential model, were developed to describe the relationship between the texture parameters and field measurements of LAI and to select the most effective texture parameters and window size. The results showed that the texture parameters influenced the accuracy of LAI estimation.

[Study on environmental and psychological risk factors for female infertility].

Objective: To investigate the environmental and psychological risk factors for female infertility and to provide a scientific basis for the prevention and control of female infertility.

Methods: In a hospital-based case-control study, a self-designed questionnaire was used to survey the cases and controls (1:1) with nation and age (± 2 years) as matching variables. Univariate and multivariate conditional logistic regression models were employed to analyze the datasets.

Synergistic effect of panobinostat and bortezomib on chemoresistant acute myelogenous leukemia cells via AKT and NF-κB pathways.

In this study, we investigated the synergistic effects of panobinostat and bortezomib on adriamycin-resistant HL60/ADR cells and refractory acute myelogenous leukemia (AML) primary cells. Combination of both agents had synergistic cytotoxicity on these cells, and increased the sensitivity of HL60/ADR cells to adriamycin. Panobinostat plus bortezomib was shown to modulate multiple apoptotic and drug metabolic related molecules, including activation of caspases, down-regulation of XIAP, Bcl-2 and MRP1.

Effects of anisodamine on the expressions of vascular endothelial growth factor and intercellular adhesion molecule 1 in experimental infusion phlebitis.

Background: Infusion phlebitis is the most common side effect of clinical intravenous drug therapy and several clinical studies have demonstrated that anisodamine can effectively prevent the occurrence of infusion phlebitis. This study was designed to investigate effects of anisodamine on the expressions of vascular endothelial growth factor (VEGF) and intercellular adhesion molecule 1 (ICAM-1) in a rabbit model of infusion phlebitis and to analyze the mechanisms of anisodamine effect on the prevention and treatment of experimental infusion phlebitis.

Methods: Twenty-four specific pathogen-free male Japanese white rabbits were randomly assigned to the control group, the model group, the magnesium sulfate group and the anisodamine group.

Magnetic resonance spectroscopy in the diagnosis of cognitive impairment in AIDS patients.

Background: The pathological abnormalities of the AIDS patients lie in the subcortical regions of the brain, specifically the deep white matter and basal ganglia, while the extent of pathology generally correlates with the severity of cognitive impairments in the white matter and basal ganglia. Brain metabolite changes of these lesions can reflect the pathological abnormalities. The purpose of this study was to assess the value of magnetic resonance spectroscopy (MRS) in the diagnosis of cognitive impairment in AIDS patients.

[Abeta(25-35) and ginsenoside Rb1 influence on the expression of GSK-3beta, CDK-5 and PP2A in differentiated neural stem cells of rats].

Objective: To explore the expression of GSK-3beta, CDK-5 and PP2A and the regulation of them by Abeta(25-35) and ginsenoside Rb1 after neural stem cells (NSCs) are transformed into neurons.

Methods: To culture NSCs from the dentate gyrus of newborn rats(24 h) hippocampus in vitro. NSCs of the third passage were induced towards neurons; the expressions of GSK-3beta(pTyr279,216), PP2A and the regulation of them by Abeta(25-35) and ginsenoside Rb1 were tested by the immunofluorescence cytochemical staining after NSCs had been induced for one week; The expressions of GSK-3beta, CDK-5, PP2A and the regulation of them by Abeta(25-35) and ginsenoside Rb1 were detected with RT-PCR.

O,O'-Diethyl {(Z)-[(2-chloro-phen-yl)(cyano)methyl-ene]amino-oxy}thio-phospho-nate.

The title mol-ecule, C(12)H(14)ClN(2)O(3)PS, has a cis configuration with respect to the C=N bond. Inter-molecular C-H⋯O inter-actions inter-connect the mol-ecules into chains along the c axis. The chains are further connected into a two-dimensional network parallel to the bc plane by weak π-π inter-actions between adjacent aromatic rings (centroid-centroid distance = 3.

[A cross-sectional case study of human immunodeficiency virus and tuberculosis co-infection in mainland China].

Objective: In order to take an insight into the profile of HIV/AIDS and tuberculosis (TB) co-infection, we made a statistic survey in 9 hospitals in mainland China. With the purpose of guiding the prevention and treatment, 241 cases with such co-infection were enrolled and the data with respect to clinical manifestations, laboratory tests, therapy and prognosis were analysed.

Methods: All indices were collected with unified questionary.

Characteristics of HIV-1-specific CD8 T-cell responses and their role in loss of viremia in children chronically infected with HIV-1 undergoing highly active antiretroviral therapy.

Background: Few studies have examined the properties of human immunodeficiency virus type 1 (HIV-1) epitope-specific cytotoxic T lymphocyte (CTL) responses in children. To address this issue, we characterized epitope-specific CTL responses and analyzed the determinants that may affect CTL responses before and after highly active antiretroviral therapy (HAART) in children with HIV-1 infection.

Methods: A total of 22 HIV-1-infected children and 23 uninfected healthy children as control were enrolled in the study.

[Coinfection with HBV and HCV in 128 AIDS patients infected through blood transmission].

Objective: To analyze the clinical features of 128 acquired immunodeficiency syndrome (AIDS) patients infected through blood transmission who were coinfected with hepatitis B virus (HBV) and hepatitis C virus (HCV).

Methods: The prevalence, liver functions, and some immunological profiles of 128 AIDS patients coinfected with HBV and HCV were retrospectively analyzed.

Results: Among the 128 AIDS patients, 107 (83.

[AIDS complicated by Pneumocystis carinii pneumonia: report of 20 cases].

Objective: To report our experience in diagnosis and treatment of AIDS complicated by Pneumocystis Carinii Pneumonia (PCP), and explore the relations between preventive medication and occurrence as well as recurrence of PCP.

Methods: The clinical characteristics of 20 patients with AIDS complicated by PCP (identified from a cohort of 109 patients with AIDS) treated in our hospital during July 2000 to May 2002 were analyzed.

Results: All the 20 cases had fever, 90 % of whom also had cough or expectoration, and chest radiography revealed bilateral interstitial changes in 80 % of the cases.