Publications by authors named "Qing-Tai Dong"
Article Synopsis
- FAM3 family genes are significant in the development of various cancers, influencing factors like prognosis, immune response, and drug sensitivity, though their exact role in pan-cancer remains unclear.
- This study analyzed data from multiple databases and conducted experiments, specifically focusing on the effects of FAM3C in pancreatic cancer, revealing that its expression significantly affects tumor characteristics and patient outcomes.
- Results showed that FAM3 family genes are differentially expressed in several cancers, correlate with immune subtypes, and that FAM3C expression increases tumor cell proliferation and invasion while decreasing apoptosis.
J Clin Lab Anal
December 2022
Article Synopsis
- Pancreatic adenocarcinoma (PAAD) is a highly malignant digestive tumor that requires the identification of differential genes and oncogene targets for early diagnosis and treatment.
- This study focuses on the role of the FAM111B gene in PAAD, finding that its expression is significantly higher in cancer tissues compared to normal tissues and is linked to poor patient prognosis.
- Increased levels of FAM111B enhance tumor cell proliferation, migration, and invasion while reducing apoptosis, suggesting it could serve as a new biomarker and therapeutic target for PAAD.
