Dry eye and corneal sensitivity after small incision lenticule extraction and femtosecond laser-assisted keratomileusis: a Meta-analysis.

Aim: To assess the corneal sensitivity and the incidences of dry eye after small incision lenticule extraction (SMILE) and femtosecond laser-assisted keratomileusis (FS-LASIK).

Methods: The Meta-analysis was performed using RevMan 5.3.

Improved picoliter-sized micro-reactors for high-throughput biological analysis.

High-throughput pyrosequencing, carried out in millions of picoliter-sized reactors on a fiber-optic slide, is known for its longer read length. However, both optical crosstalk (which reduces the signal-to-noise ratio of CCD images) and chemical retention adversely affect the accuracy of chemiluminescence determination, and ultimately decrease the read length and the accuracy of pyrosequencing results. In this study, both titanium and oxidized aluminum films were deposited on the side walls and upper faces of micro-reactor slides to enhance optical isolation; the films reduced the inter-well crosstalk by one order of magnitude.