Nootkatone Improves Chronic Unpredictable Mild Stress-Induced Depressive-Like Behaviors by Repressing NF-κB/NLRP3-Mediated Neuroinflammation.

Objective: To explore the effect of nootkatone (NKT) on chronic unpredictable mild stress (CUMS)-induced depressive-like behaviors and the mechanism underlying NKT improving the depressive-like behaviors.

Methods: The CUMS-induced depression model was established in mice. Fifty mice were randomized into 5 groups (n=10) in accordance with a random number table: control group, CUMS group, CUMS + NKT (6 mg/kg) group, CUMS + NKT (12 mg/kg) group, and CUMS + ketamine group.

[A brief talk on the embodiment of Three-Layer thought in the science of acupuncture and moxibustion].

Three-Layer thought is an important proposition in Chinese traditional philosophy. This thought embodies the Chinese people's cosmology and methodology and exerts a far-reaching influence on various aspects of Chinese culture. The embodiment of Three-Layer thought in the theory and practice of acupuncture and moxibustion from naming of acupoints, principles of treatment, needling instruments, prescription of acupoints as well as needling techniques is elaborated and briefly analyzed.

[Synthesis and spectral properties of a novel fluorinated triphenylamine derivative].

A novel fluorinated triphenylamine derivative, N,N,N',N'-tetraphenyl-[2', 2", 3', 3", 5', 5", 6', 6"octafluoro-p-quater-phenyl]-4,4"'-diamine (OFTPA), was designed and synthesized via the palladium-catalyzed Suzuki coupling reaction of 4,4'-di-bromooctafluorobiphenyl with triphenylamine-4-boronic acid (yield: 67%). Its molecular structure was characterized by elemental analysis, melting points, FTIR and 1H NMR spectroscopy, and the main FTIR absorption peaks and 1H NMR spectral bands of the compound were assigned. The energy level structure and photoluminescence properties of OFTPA were investigated by UV-Vis absorption, fluorescence spectroscopy and cyclic voltammetry (CV).

[Analysis of the academic advantage of Huangdi Neijing based on future medical trends].

Combined with the transformation of modern medicine, the author analyzed the instructional value of the academic theories proposed in the Huangdi Neijing. These theories include medical modes varying from medicine focusing on disease to medicine focusing on health, from biomedicine to ecological medicine, from the treatment of conditions to the treatment of the patient, from group therapy to individual therapy, and from disease treatment to holistic treatment. Through analysis of these treatment modalities the implications of their possible use in future medicine can be assessed.

[Methods for clinical study of Nei Jing].

Nei Jing or Canon of Medicine established the theoretical system of traditional Chinese medicine, and lay the foundation for the development of clinical traditional Chinese medicine. The author holds that the researchers should study the Canon of Medicine according to clinical practice so as to find its new and valid academic values. At present, the approaches to clinical study of Canon of Medicine include case research, large sample retrospective verification, epidemiological survey and the exploration of case reports in ancient times and so on.

[A new Bayesian reconstruction algorithm for PET images based on correction of the detected sinogram data].

Objective: To improve Bayesian reconstruction of positron-emission tomography (PET) images by devising a novel coupled feedback (CF) iterative model.

Methods: The CF iterative algorithm was applied to update the noisy detected emission sinogram data using the latest reconstructed image in the iterative process of PET reconstruction. The relevant operations included linear filtering, wiener filtering, and projection of the reconstructed images.