Silencing lncRNA TUG1 Alleviates LPS-Induced Mouse Hepatocyte Inflammation by Targeting miR-140/TNF.

Hepatitis is a major public health problem that increases the risk of liver cirrhosis and liver cancer. Numerous studies have revealed that long non-coding RNAs (lncRNAs) exert essential function in the inflammatory response of multiple organs. Herein, we aimed to explore the effect of lncRNA TUG1 in LPS-induced hepatocyte inflammation response and further illuminate the underlying mechanisms.

A comparative research on obesity hypertension by the comparisons and associations between waist circumference, body mass index with systolic and diastolic blood pressure, and the clinical laboratory data between four special Chinese adult groups.

Background: The obesity-hypertension pathogenesis is complex. From the phenotype to molecular mechanism, there is a long way to clarify the mechanism. To explore the association between obesity and hypertension, we correlate the phenotypes such as the waist circumference (WC), body mass index (BMI), systolic blood pressure (SB), and diastolic blood pressure (DB) with the clinical laboratory data between four specific Chinese adult physical examination groups (newly diagnosed untreated just-obesity group, newly diagnosed untreated obesity-hypertension group, newly diagnosed untreated just-hypertension group, and normal healthy group), and the results may show something.

Validation of the Simplified Chinese-character Version of the International Physical Activity Questionnaire-Long Form in Urban Community-dwelling Adults: a Cross-sectional Study in Hangzhou, China.

Objective: To assess the test-retest reliability and criterion validity of the Simplified Chinese-character version of the International Physical Activity Questionnaire Long form (IPAQ-L) in urban community-dwelling adults in Hanghzou, China.

Methods: A total of 158 eligible participants aged 25-59 years from 6 neighbourhoods in two central districts of Hangzhou completed the IPAQ-L questionnaire twice within a 7-day interval. Half of the subjects wore pedometers during the first 7 days.

Effects of cytomegalovirus infection on the prognosis of inflammatory bowel disease patients.

The aim of the present study was to investigate the effects of cytomegalovirus (CMV) infection on the prognosis of inflammatory bowel disease (IBD). Various databases were searched using a combination of keywords associated with CMV infection and IBD. Subsequent to the selection of relevant studies in line with strict inclusion and exclusion criteria, a meta-analysis was conducted using the Stata 12.

Family influences on physical activity and sedentary behaviours in Chinese junior high school students: a cross-sectional study.

Background: Family influence plays an important role in a child's physical activity (PA). This study aimed to describe the level of moderate to vigorous intensity physical activity (MVPA) and sedentary behaviours among Chinese junior high school students and examine the associations between different types of family influence and MVPA or sedentary behaviours.

Methods: Participants of two independent cross-sectional surveys, conducted in 2009 and 2011, were students in Grade 7 and 9 from all junior high schools in Hangzhou, China.

Analysis of cancer incidence in Zhejiang cancer registry in China during 2000 to 2009.

Objective: The Zhejiang Provincial Cancer Prevention and Control Office collected cancer registration data during 2000 to 2009 from 6 cancer registries in Zhejiang province of China in order to analyze the cancer incidence.

Methods: Descriptive analysis included cancer incidence stratified by sex, age and cancer site group. The proportions and cumulative rates of 10 common cancers in different groups were also calculated.

Association between perceived urban built environment attributes and leisure-time physical activity among adults in Hangzhou, China.

Background: Neighborhood built environment may influence residents' physical activity, which in turn, affects their health. This study aimed to determine the associations between perceived built environment and leisure-time physical activity in Hangzhou, China.

Methods: 1440 participants aged 25-59 were randomly selected from 30 neighborhoods in three types of administrative planning units in Hangzhou.

Objective assessment of urban built environment related to physical activity--development, reliability and validity of the China Urban Built Environment Scan Tool (CUBEST).

Background: Some aspects of the neighborhood built environment may influence residents' physical activity, which in turn, affects their health. This study aimed to develop an urban built environment evaluation tool and conduct necessary reliability and validity tests.

Methods: A 41-item urban built environment scan tool was developed to objectively assess the neighborhood built environment features related to physical activity.

[Evaluation on the effect of intervention strategies regarding lifestyle-health promotion among community medical staff in Hangzhou city].

Objective: To investigate the effect of workplace intervention programs related with health-promoting lifestyles among community medical staff members in the communities of Hangzhou city.

Methods: Three representative districts including Xiacheng, Gongshu and Westlake were chosen and all the community medical staff was involved in the study. Questionnaire survey was applied to collect the information from all the community medical staff.

[Relations between attitude and practice of smoking and the training program regarding tobacco control among community medical staff members in Hangzhou, Zhejiang province].

Objective: To investigate the relations between training and both the attitude and practice on smoking control among community medical staff members in Hangzhou, Zhejiang province.

Methods: Three representative districts including Xiacheng, Gongshu and Westlake were chosen from Hangzhou city. Questionnaire survey was applied to collect information from the related community medical staff members.

A community-based multilevel intervention for smoking, physical activity and diet: short-term findings from the Community Interventions for Health programme in Hangzhou, China.

Background: To assess the short-term impact of a comprehensive, community-based multilevel intervention on knowledge, beliefs and practices with respect to smoking, physical activity and diet in Hangzhou, China.

Methods: A non-randomised, controlled, before-after quasi-experimental trial was conducted in two intervention areas and one comparison area. The intervention built on a socioecological framework and took place across four settings: neighbourhoods, schools, workplaces and community health centres.

[Assessment on the short-term impact regarding the community-based interventions to improve physical activities in three urban areas of Hangzhou city].

Objective: To evaluate the short-term impact of comprehensive community based intervention on physical activity (PA) of adults living in the three urban communities of Hangzhou city.

Methods: Within the framework of Community Interventions for Health (CIH) Program, a community trial was conducted in two urban areas (Xiacheng district and Gongshu district)and an urban area(Xihu district)as control, by a parallel comparison and random grouping based quasi-experimental design. Two independent questionnaire-based surveys of cross-sectional samples in the intervention and comparison areas were used to assess the short-term impact of the intervention program.

[Changes in knowledge and behavior related to tobacco consumption among urban population before and after the enforcement of the Smoke Control Ordinance in Public Places of Hangzhou in 2010].

Objective: To examine the changes in tobacco related knowledge, smoking habit and the amount if environmental tobacco smoke (ETS) among urban population before and after the enforcement of the Smoke Control Ordinance in Public Places of Hangzhou in March 2010.

Methods: Two independent cross-sectional surveys were conducted on random samples from adults aged 18 - 64 years in three districts of Hangzhou city between two petiods: October 2008 to August 2009 and June 2011 to February 2012.

Results: A total of 2016 adults at the initial stage and 2016 adults during the follow-up program completed the survey.

[Fruit and vegetable consumption and related influencing factors among urban junior students in Hangzhou].

Objective: To explore the fruit and vegetable (FV) consumption and related influencing factors among urban junior students in Hangzhou.

Methods: In a cross-sectional study, a self-administered questionnaire was used to assess the frequency and amount of FV consumption as well as related socio-demographic characteristics. Logistic regression method was applied to study other factors related to the amount of vegetables consumption ≥ 21 servings and fruit consumption ≥ 14 servings per week.

[Behavior and knowledge on physical activity among urban junior students in Hangzhou].

Objective: To study the status of physical activity (PA) and sedentary behaviors and relevant knowledge to it among junior students.

Methods: In a cross-sectional study, a self-administered questionnaire was used to assess the PA, sedentary behaviors and relevant knowledge on 4549 eligible urban junior students.

Results: Among the 4549 junior students, only 7.

[Prevalence rate regarding the completion of 'recommended physical activities' and related influencing factors among junior students in 3 urban districts of Hangzhou].

Objective: To explore the rate on completion of the recommended physical activities and its correlates among junior students in 3 urban districts of Hangzhou.

Methods: Describing the range on completion of the recommended physical activities and analyze its related demographic, cognitive and environmental factors with logistic regression model among 3867 juniors students.

Results: 7.

[Study on knowledge, attitudes and use of the pre-packaged food nutrition labeling in Hangzhou supermarket consumers in 2010].

Objective: To study the prevalence rates of knowledge, attitudes and use of the nutrition labeling and related influential factors in Hangzhou supermarket consumers.

Methods: Using a self-developed survey questionnaire, randomly selected customers were conducted a face-to-face interview program in a large supermarket of Hangzhou city.

Results: 586 people were interviewed, including 202 males and 384 females, with the mean age as 41.

[Application of health vignettes in correcting self-reported health condition].

To introduce the application of vignettes in the survey on health condition, we took the Hangzhou health survey as an example. We tried to find the respondents' health judgment standard by using vignettes first and discovered the population's demographic characteristics as sex, age, years of schooling and income etc. could influence the self-reported health condition on the response category cut-points.

[Application of a simple random sampling method on surveys at the community level].

Objective: To study the feasibility of a simple random sampling on surveys at the community level and to evaluate the quality of samples under survey.

Methods: A simple random sample of households was taken, based on the electronic listings of community households from Gongshu and Xiacheng districts of Hangzhou city. One of the adults aged 18 to 64 years in the sampled households was identified with KISH method to finish a questionnaire survey.

[Study on the risk factors of injuries among children at school age, from the families of migrant workers in Hangzhou city].

Objective: To explore the risk factors of injuries among school aged children from migrant workers' families, in Hangzhou.

Methods: A cross-sectional survey on 3582 students from eight separate schools in which, four were set for migrant workers' families and the other four were for families of permanent residents. Stratified cluster random sampling method was used.

[A case-crossover study on the relationship between air pollution and acute onset of cerebral hemorrhage in Hangzhou city].

Objective: To explore the relationship between air pollution and acute onset of cerebral hemorrhage in Hangzhou.

Methods: Time-stratified case-crossover study was used to analyze the effect of aerosol optical depth (AOD), PM(10), SO(2) and NO(2) on the acute onset of cerebral hemorrhage. Conditional logistic regression was used to estimate the odds ratios (ORs) and their 95% confidence intervals (CIs) in relation to an increase of one unit of AOD and 10 microg/m(3) of air pollutants.

[A case-crossover study on air pollutants and the mortality of stroke].

Objective: To investigate the short-term effect of particulate matter in air on the mortality of stroke.

Methods: Using time-stratified case-crossover study design, an association was examined between stroke mortality and particulate matter with aerodynamic diameter of < 10 microm (PM10) of 2002 - 2004 in Hangzhou city. Meanwhile, the acute health effect of other gaseous pollutants (sulfur dioxide, SO2 and nitrogen dioxide, NO2) was also analyzed.