Publications by authors named "Qing-Min Li"
Seventeen novel 2-(5-amino-1-(substituted sulfonyl)-1-1,2,4-triazol-3-ylthio)-6- isopropyl-4,4-dimethyl-3,4-dihydronaphthalen-1(2)-one compounds were synthesized from the abundant and naturally renewable longifolene and their structures were confirmed by FT-IR, NMR, and ESI-MS. The in vitro cytotoxicity of the synthesized compounds was evaluated by standard MTT assay against five human cancer cell lines, i.e.
View Article and Find Full Text PDFArticle Synopsis
- The study focuses on the Wnt/β-catenin signaling pathway's role in hepatocellular carcinoma (HCC) and its association with specific gene polymorphisms in the Chinese Han population.
- Researchers genotyped 20 single nucleotide polymorphisms in 320 HCC patients, 320 patients with chronic hepatitis but without HCC, and 320 healthy controls to explore these associations.
- Key findings revealed that certain polymorphisms in the WNT2 and CTNNB1 genes are significantly linked to HCC susceptibility and progression, particularly in advanced stages of the disease.
Background: Glial cell line-derived neurotrophic factor (GDNF) is a small protein that potently promotes the survival of many types of neurons. Detection of GDNF is vital to monitoring the survival of sympathetic and sensory neurons. However, the specific method for GDNF detection is also un-discovered.
View Article and Find Full Text PDF