Publications by authors named "Qing-Ling Lin"
Background/purpose: Ludwig's angina (LA) still presents regularly and various characteristics are documented, but patients admitted to the Intensive Care Unit (ICU) has not been studied. The purpose of this study was to investigate the clinical characteristics and outcomes of patients with LA who were admitted to ICU.
Materials And Methods: We retrospectively reviewed all 29 patients with LA who were admitted to the ICU of a university hospital from January 2013 to October 2018.
Article Synopsis
- Significant differences exist in the expression of the urokinase plasminogen activator (uPA) system between cancer tissues and normal tissues, but its effectiveness as a prognostic biomarker for non-small cell lung cancer (NSCLC) is still uncertain.
- A systematic review and meta-analysis of 11 studies involving 937 NSCLC patients showed that increased levels of uPA and PAI-1 did not significantly correlate with poor overall survival (OS), while reduced PAI-2 also had no significant association with OS.
- In contrast, higher expression of the uPA receptor (uPAR) was significantly linked to poor OS, suggesting that uPAR could serve as a promising clinical biomarker for assessing NSCLC prognosis and guiding targeted treatments.