Adsorptive properties of graphene oxide on vitamin B12 and their effect on the promotion of peripheral nerve regeneration.

Objectives: To observe whether Graphene oxide (GO) can absorb vitamin B12 (VB12) and Decellularized scaffold - acellular nerve allograft (ANA) modified GO-VB12 promote the repair of ischiadic nervus defects in a rat model.

Methods: The adsorption of GO on vitamin and the optimum adsorption conditions were investigated by single factor experiment. The adsorption properties of the material were observed by scanning electron microscopy (SEM) and energy dispersive spectrometer (EDS) to determine the success of adsorption on VB12.