Publications by authors named "Qing Nan Zhou"

Article Synopsis
  • The study investigates the relationship between the oral microbiome and severe early childhood caries (S-ECC) by comparing the dental plaque of children before and after treatment.
  • A total of 40 children aged 3 to 5 underwent dental treatment in two different settings: under general anaesthesia (C1) and outpatient (C2), with microbiome analysis conducted at multiple time points post-treatment.
  • Results showed increased microbial diversity after treatment in the outpatient group and highlighted changes in specific bacteria’s abundance related to treatment type and timing, suggesting treatment impacts the oral microbiome composition.
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Background: The tumor microenvironment (TME) plays a crucial role in tumorigenesis, progression, and therapeutic response in many cancers. This study aimed to comprehensively investigate the role of TME in colorectal cancer (CRC) by generating a TMEscore based on gene expression.

Methods: The TME patterns of CRC datasets were investigated, and the TMEscores were calculated.

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Background: Oxaliplatin-based chemotherapy is the first-line treatment for colorectal cancer (CRC). Long noncoding RNAs (lncRNAs) have been implicated in chemotherapy sensitivity. This study aimed to identify lncRNAs related to oxaliplatin sensitivity and predict the prognosis of CRC patients underwent oxaliplatin-based chemotherapy.

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