Publications by authors named "Qing Min Wei"

Background: There is scant data on the association of the Pulsed wave-Doppler tissue imaging (PW-DTI)-derived tricuspid lateral annular peak systolic velocity (S') and poor short-term prognosis of patients with acute decompensated heart failure (ADHF).

Patients And Methods: A total number of 732 participants from the Heb-ADHF registry in China were divided into three groups according to the corresponding status of tricuspid S'. Demographic characteristics, comorbidities, physical examinations, lab tests, and medications were compared among the different groups.

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Background: Few prognostic risk scores (PRSs) have been routinely used in acute decompensated heart failure (ADHF). We, therefore, externally validated three published PRSs (3A3B, AHEAD, and OPTIME-CHF) and derived a new PRS to predict the short-term prognosis in ADHF.

Methods: A total of 4550 patients from the Heb-ADHF registry in China were randomly divided into the derivation and validation cohorts (3:2).

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Article Synopsis
  • Thirteen transition metal complexes were synthesized and characterized, with a focus on their cytotoxic effects on A549/DDP cancer cells using various analytical techniques.
  • Complexes 10-13 exhibited significantly stronger anti-cancer activity compared to complexes 1-9, with IC values ranging from 0.97 to 3.31 μM.
  • Complexes 11 and 13 specifically induced apoptosis and autophagy through mitochondrial dysfunction, highlighting their potential as effective treatments for A549/DDP xenografts.
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Objective: To evaluate efficacy, safety and feasibility of targeted intracoronary injection using pro-urokinase combined with anisodamine (TCA) versus thrombus aspiration (TA) in ST-elevation myocardial infarction (STEMI) patients with high thrombus loads.

Background: The best method of avoiding thrombus detachment and stroke in PCI patients with high thrombus loads has not yet been established.

Methods: STEMI patients receiving coronary artery angiography or percutaneous coronary intervention (CAG/PCI) with thrombus grade ≥ 3 from January 1, 2017 to June 30, 2018 were randomly assigned to targeted intracoronary thrombolysis (pro-urokinase and anisodamine via catheter (TCA) group), or the TA group which followed the standard thrombus aspiration procedure.

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Two novel platinum(ii) complexes, [PtCl2(H-MeOBC)(DMSO)] (Pt1) and [Pt2Cl3(MeOBC)(DMSO)2] (Pt2), with 3-(2'-benzimidazolyl)-8-methoxycoumarin (H-MeOBC) as the ligand were synthesized and evaluated for their antiproliferative activity. Among all the tumor cells, dual-Pt(ii) complex Pt2 exhibited the most potent activity, with an IC50 value of 0.5 ± 0.

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Aims: Ovarian cancer is the fifth most deadly cancer in women, and is usually diagnosed too late. Exploring specific and sensitive biomarkers will be helpful to early detection and will improve the survival rates of ovarian cancer patients.

Main Methods: Realtime PCR was used to detect the expression of miR-376a.

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  • LaF3 : Tba3+, Ce3+ nanocrystals were synthesized using a hydrothermal method with cetyltrimethyl ammonium bromide (CTAB), investigating how pH, Ce3+/Tb3+ ratio, and reaction time affect their luminescent properties.
  • XRD analysis confirmed that the samples have a hexagonal phase with slight shifts in diffraction peaks, indicating isomorphous substitution of La3+ with the rare earth ions.
  • The results showed that the fluorescence intensities vary with Ce3+/Tb3+ ratios and pH, achieving optimal green emission at a Ce3+/Tb3+ ratio of 4 and color purity improves with increased reaction time, particularly at pH 9
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  • The study investigates the synthesis of LaVO4: Dy3+ nanorods using a solvothermal method, with a focus on varying pH levels in an ethanol-water solution.
  • Characterization techniques like X-ray diffraction and electron microscopy reveal a phase transition and a shift from irregular nanoparticles to one-dimensional nanorods as pH increases.
  • The nanorods show a decrease in band gap energy and exhibit strong yellow and blue emissions, indicating promising optical properties for potential applications.
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Background: Many basic and clinical studies have proved that anisodamine can produce significant effect on relieving microvascular spasm, improving and dredging the coronary microcirculation. It may be beneficial to the improvement of slow-reflow phenomenon (SRP) following percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI). So we investigated the effect of intracoronary administration of anisodamine on SRP of infarct related artery (IRA) following primary PCI in patients with ST segment elevated acute myocardial infarction (STEAMI).

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Background: The infraclavicular subclavian route is commonly used for insertion of permanent pacing leads. However, the subclavian vein route may at times be a very difficult way to gain access to the heart.

Objective: To explore a new route to reliably and safely insert pacing leads.

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