The tricarboxylic acid cycle is inhibited under acute stress from carbonate alkalinity in the gills of Eriocheir sinensis.

Owing to population growth and environmental pollution, freshwater aquaculture has been rapidly shrinking in recent years. Aquaculture in saline-alkaline waters is a crucial strategy to meet the increasing demand for aquatic products. The Chinese mitten crab is an important economic food in China, but the molecular mechanism by which it tolerates carbonate alkalinity (CA) in water remains unclear.

Glutamate-pantothenate pathway promotes antibiotic resistance of .

Although cellular metabolic states have been shown to modulate bacterial susceptibility to antibiotics, the interaction between glutamate (Glu) and chloramphenicol (CAP) resistance remains unclear because of the specificity of antibiotics and bacteria. We found that the level of Glu was upregulated in the CAP-resistant strain of according to a comparative metabolomics approach based on LC-MS/MS. Furthermore, we verified that exogenous metabolites related to Glu, the tricarboxylic acid (TCA) cycle, and glutathione (GSH) metabolism could promote CAP resistance in survival assays.

Progress in the application of Enterococcus faecium in animal husbandry.

As a probiotic, enterococcus faecium (E. faecium) has the characteristics of high temperature resistance, gastric acid resistance, bile salt resistance, etc. It can also effectively improve animal performance and immunity and improve the animal's intestinal environment, so in recent years it has been more widely used in the livestock industry.

Transcriptome analysis in the spleen of Northern Snakehead (Channa argus) challenged with Nocardia seriolae.

Northern snakehead (Channa argus) is an indigenous fish species and is one of popularly cultured snakeheads in China and other Asian countries. Unfortunately, Nocardia seriolae infections have caused considerable losses in the snakehead aquaculture industry. However, the infectivity and the immune response induced by N.

Metabolites in the TCA Cycle Promote Resistance to Chloramphenicol of .

Antibiotic-resistant bacteria are a serious threat to human and animal health. Metabolite-enabled eradication of drug-resistant pathogens is an attractive strategy, and metabolite adjuvants, such as fumarate, are used for restoring the bactericidal ability of antibiotics. However, we show that metabolites in the TCA cycle increase the viability of against chloramphenicol (CAP), based on the survival assay of differential metabolites identified by LC-MS/MS.

The complete mitochondrial genome of golden yellow snakehead fish, .

We sequenced and characterized the complete mitochondrial genome of golden yellow snakehead fish, The mitogenomes contained the typical complement of 13 protein-coding genes, 22 transfer RNAs (tRNAs), 2 ribosomal RNAs (rRNAs), and a non-coding control region. They share the same gene arrangement pattern that was identical with most vertebrates. The entire mitochondrial DNA molecule of golden yellow snakehead fish was 16,558 bp long.

The complete mitochondrial genome of two different colour (Cypriniformes, Cyprinidae).

We sequenced and characterized the complete mitochondrial genome from normal colour (grey black) and mutant colour (orangey red) of . Both mitogenomes contained the typical complement of 13 protein-coding genes, 22 transfer RNAs (tRNAs), two ribosomal RNAs (rRNAs), and a non-coding control region. They share the same gene arrangement pattern that was identical with most vertebrates.

Apoptosis of non-tumor cells contributes to increased serum cytochrome c level in a neuroblastoma xenograft model.

Background: Neuroblastoma (NB) is one of the most common malignant solid tumors of childhood. It is still not clear whether the apoptosis of tumor cells or the non-tumor cells contributes to the increase of concentration of cytochrome c (Cyt c) in the serum of the cancer patients. The aim of this research was to identify the source of the Cyt c in the serum when the tumor grows up by subcutaneous inoculation of human NB cells into nude mice.

Multi-dimensional transition-metal coordination polymers with 5-nitro-1,2,3-benzenetricarboxylic acid exhibiting ferro-/antiferromagnetic interactions.

Six transition metal coordination polymers, [Cu(3)(nbta)(2)(bipy)(2)(H(2)O)(2)] x 2 H(2)O (1), [Cu(3)(nbta)(2)(bpp)(2)(H(2)O)(2)] x 2 H(2)O (2), [Co(3)(nbta)(2)(bipy)(3)(H(2)O)(2)] x 2 H(2)O (3), [Co(3)(nbta)(2)(bpp)(2)(H(2)O)(2)] (4), [Ni(2)(Hnbta)(2)(bipy)(2)(H(2)O)(2)] (5) and [Ni(3)(nbta)(2)(bpa)(3)(H(2)O)(2)] x 2 H(2)O (6) (H(3)nbta = 5-nitro-1,2,3-benzenetricarboxylic acid, bipy = 4,4'-bipyridine, bpa = 1,2-bis(4-pyridyl)ethane, bpp = 1,3-bis(4-pyridyl)propane), have been hydrothermally synthesized by the reactions of Cu(II), Co(II) and Ni(II) salts with H(3)nbta in the presence of dipyridyl-type co-ligands, respectively. Their structures were determined by single-crystal X-ray diffraction analyses and further characterized by elemental analyses, IR spectra, and TG analyses. Compounds 1-4 and 6 exhibit 3D pillared-layer structures while compound 5 has a 2D layer.