Publications by authors named "Qinbao Lu"

Objective: To describe the trends in the incidence of hand, foot and mouth disease (HFMD) before, during, and after China's Coronavirus Disease (COVID) control policies, and to interpret the influence on HFMD incidence at different control stages in Zhejiang Province.

Methods: We collected data on HFMD cases in Zhejiang between 2014 and 2023. We compared the constituent ratios of cases at different COVID control stages by sex, age, child groups, and pathogens and weekly seasonal indices to observe seasonal variations in the incidence of HFMD.

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Article Synopsis
  • China, especially Zhejiang Province, is a major hotspot for scrub typhus, but there is uncertainty in reported case numbers which complicates understanding its epidemiology.
  • Researchers gathered data on scrub typhus cases from 2016 to 2023 and used statistical methods to estimate incidence and identify key factors influencing its occurrence at the county level.
  • From the data, 2,678 cases were reported with a low fatality rate; incidence varied seasonally and geographically, revealing underreported cases and fluctuation in incidence across different regions of Zhejiang.
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Background: Syphilis has caused epidemics for hundreds of years, and the global syphilis situation remains serious. The reported incidence rate of syphilis in Zhejiang Province has ranked first in the province in terms of notifiable infectious diseases for many years and is the highest in China. This study attempts to use the scaling law theory to study the relationship between population size and different types of syphilis epidemics, while also exploring the main driving factors affecting the incidence of syphilis in different regions.

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Background: Influenza infection causes a huge burden every year, affecting approximately 8% of adults and approximately 25% of children and resulting in approximately 400,000 respiratory deaths worldwide. However, based on the number of reported influenza cases, the actual prevalence of influenza may be greatly underestimated. The purpose of this study was to estimate the incidence rate of influenza and determine the true epidemiological characteristics of this virus.

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Background: Zhejiang, ranked in the top three in HFMD (hand, foot, and mouth disease) incidence, is located in the Yangtze River Delta region of southeast China. Since 2016, the EV71 vaccine has been promoted in Zhejiang Province. This study aimed to investigate the trend and seasonal variation characteristics of HFMD from 2010 to 2021 and estimate the reduction in enterovirus 71 infection after vaccine use.

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Background: Zhejiang Province is one of the five provinces in China that had the highest incidence of novel coronavirus disease (COVID-19). Zhejiang, ranked fourth highest in COVID-19 incidence, is located in the Yangtze River Delta region of southeast China. This study was undertaken to identify the space-time characteristics of COVID-19 in Zhejiang.

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Background: Zhejiang Province has the fifth-highest incidence of severe fever with thrombocytopenia syndrome (SFTS) in China. While the top four provinces are all located in northern and central China, only Zhejiang Province is located in the Yangtze River Delta region of southeast China. This study was undertaken to identify the epidemiological characteristics of SFTS in Zhejiang from 2011 to 2018.

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Objective: The aim of this study was to analyze the trends and epidemiological characteristics of scarlet fever in Zhejiang Province in 2004-2018, intending to provide a basis for targeted prevention and control of this disease.

Method: We collated the epidemiological data for cases of scarlet fever from the China Information System for Disease Control and Prevention (CISDCP) in Zhejiang province between 1 January 2004 and 31 December 2018. Descriptive statistical analysis was used to analyze epidemiological characteristics of scarlet fever, whereas the Getis-Ord Gi* statistic was used to determine the hotspot incidence of scarlet fever.

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Background: The number of dengue fever (DF) cases and the number of dengue outbreaks have increased in recent years in Zhejiang Province, China. An unexpected dengue outbreak was reported in Hangzhou in 2017 and caused more than one thousand dengue cases. This study was undertaken to evaluate the effectiveness of the actual control measures, estimate the proportion of inapparent infections during this outbreak and simulate epidemic development based on different levels of control measures taking inapparent infections into consideration.

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  • The study examines the morbidity and mortality rates of notifiable diseases in children aged 0-14 in Zhejiang Province from 2008 to 2017, reporting 1,994,740 cases and 266 deaths.
  • The average morbidity rate was 2502.87 per 100,000 children, with boys experiencing higher rates (2886.98) than girls (2072.16).
  • Key diseases identified include hand-foot-and-mouth disease and infectious diarrheal diseases, highlighting the need for improved prevention, surveillance, and vaccination efforts.
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  • Zhejiang Province has a high rate of haemorrhagic fever with renal syndrome (HFRS), with a total of 4,836 cases and 15 fatalities reported from 2007 to 2017.
  • Data analysis using methods like joinpoint regression and ARIMA models showed a significant decreasing trend in incidence rates, with male farmers and middle-aged individuals being the most affected demographics.
  • Geographic analysis revealed 54 clusters of high incidence, indicating the need for tailored prevention strategies in different regions based on local factors influencing HFRS transmission.
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To explore epidemiological characteristics of imported acute infectious diseases between 2011 and 2016 in Zhejiang province, China. Data of imported infectious diseases from 2011 to 2016 was collected from the China Information System for Disease Control and Prevention in Zhejiang province, and subsequently analyzed for epidemiological characteristics. A survey was conducted to investigate clinicians' abilities to diagnose these diseases in Zhejiang province.

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Background: The five-wave epidemic of H7N9 in China emerged in the second half of 2016. This study aimed to compare the epidemiological characteristics among the five waves, estimating the possible infected cases and inferring the extent of the possible epidemic in the areas that have not reported cases before.

Methods: The data for the H7N9 cases from Zhejiang Province between 2013 and 2017 was obtained from the China Information Network System of Disease Prevention and Control.

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Background: In China, waterborne outbreaks of infectious diarrheal disease mainly occur in schools, and contaminated well water is a common source of pathogens. The objective of this review was to present the attack rates, durations of outbreak, pathogens of infectious diarrheal disease, and sanitary conditions of wells in primary and secondary schools in China, and to analyze risk factors and susceptibility of school children.

Methods: Relevant articles and reports were identified by searching PubMed, Web of Science, China National Knowledge Infrastructure, China Information System for Disease Control and Prevention, and the Chinese Field Epidemiology Training Program.

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Objectives: More than 900 students and teachers at many schools in Jiaxing city developed acute gastroenteritis in February 2014. An immediate epidemiological investigation was conducted to identify the pathogen, infection sources and route of transmission.

Methods: The probable cases and confirmed cases were defined as students or teachers with diarrhoea or vomiting present since the term began in February 2014.

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Objective: To analyze and evaluate the application of China Infectious Diseases Automated-alert and Response System(CIDARS)in Zhejiang province.

Methods: Data through the monitoring program in 2012 was analyzed descriptively and compared with the incidence data in the same period as well information related to public health emergency events.

Results: A total of 14 292 signals were generated on 28 kinds of infectious diseases in the system, in Zhejiang province.

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Article Synopsis
  • - The study aimed to assess the performance of the China Infectious Disease Automated-alert and Response System (CIDARS) in Zhejiang province over a two-year period, analyzing how well it detected and responded to infectious disease alerts.
  • - During the evaluation, CIDARS generated 26,446 signals related to 17 diseases, with a high response rate of 99.95%, but only 0.90% were confirmed as suspected events after initial verification.
  • - The system showed a sensitivity of 69.77% and a low false alarm rate of 1.39%, indicating it could effectively warn about outbreaks, but improvements are needed to reduce false positives and enhance data quality for better accuracy.
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