Development and validation of a nomogram for primary duodenal carcinoma: a multicenter, population-based study.

This study aimed to develop a predictive model for patients with duodenal carcinoma. Duodenal carcinoma patients from the Surveillance, Epidemiology, and End Results database (2010-2015) and the First Affiliated Hospital of Nanchang University (2010-2021) were enrolled. A nomogram was constructed according to least absolute shrinkage and selection operator regression analysis, the Akaike information criterion approach and Cox regression analysis.

Monitoring frequency of interferon gamma release assay for tuberculosis surveillance following infliximab therapy in patients with Crohn's disease.

Objective: To characterize the pattern of positive conversion of interferon gamma release assay (IGRA) in patients with Crohn's disease (CD) during infliximab therapy in China, which has a high burden of tuberculosis.

Methods: Eligible patients with CD who received serial IGRA screening during infliximab therapy from January 2015 to March 2020 were retrospectively included. The positive conversion rate of IGRA and the risk of subsequent tuberculosis of the patients were analyzed.

Drug-resistant bacteria screening and patient barrier precautions are associated with decreased neonatal nosocomial infection.

Introduction: Neonates are at high risk of nosocomial infections, especially in developing countries. This study aimed to examine the effectiveness of drug-resistant bacteria (DRB) screening in combination with patient barrier precautions in controlling nosocomial infections in neonatal wards.

Methodology: The clinical data of neonates admitted to the Mianyang Central Hospital, Mianyang, China in 2010 and 2012 were retrospectively analyzed.

A mathematical model for predicting putative association between E2/T ratio and the development of benign prostate hyperplasia in rats.

Benign prostatic hyperplasia (BPH) develops more likely with increasing age and changing serum concentrations of circulating estradiol (E2) and/or testosterone (T). In this study, we explored the relationship between serum E2/T ratio and BPH risk in rats by fitting a mathematical model. A total of 176 rats were randomized to one of the following treatment groups: normal control, castrated control, and 20 more groups of castrated animals treated with increasing dose combinations of T and E2, once daily for 30 days.