Determination of the contents of five heavy metals in artificial musk.

Objective: To evaluate the safety of artificial musk by determining its content of five hazard heavy metals.

Method: The contents of Pb, Cd,As,Hg,and Cu in artificial musk were detected using inductively coupled plasma-mass spectrometry.

Result: The contents of Pb,Cd,As,Hg,and Cu was less than 0.

Detection of artificial musk in Xihuangwan by gas chromatography-mass spectrometery.

Objective: To control the quality of Xihuangwan by improving the qualitative detection of artificial musk inside this pill.

Method: The qualitative detection of artificial musk was carried out by gas chromatography-mass spectrometery(GC-MS).

Result: The established GC-MS successfully detected artificial musk in Xihuangwan.

Effect of artificial musk aqueous extract on the expressions of inflammatory mediators released from lipopolysaccharide-stimulated RAW264.7 cells.

Objective: To identify the anti-inflammatory effects of artificial musk aqueous extract(AME)on lipopolysaccharide-stimulated cytokines secreted or released by RAW264.7 cells.

Methods: Cytokines including interleukin(IL)-6,IL-10,and tumor necrosis factor Α were determined using cytokine enzyme-linked immunosorbent assay kits.