Publications by authors named "Qin-Wei Lu"
Ubiquitin-specific protease 3 (USP3), a kind of cysteine protease, is a crucial family member of deubiquitinating enzymes. USP3 is aberrantly expressed in several tumors, which may contribute to cancer progression. However, the role of USP3 in gallbladder cancer (GBC) is still unknown.
View Article and Find Full Text PDFBackground: Hepatocellular carcinoma (HCC) exhibits high invasiveness and mortality rates, and the molecular mechanisms of HCC have gained increasing research interest. The abnormal DNA damage response has long been recognized as one of the important factors for tumor occurrence and development. Recent studies have shown the potential of the protein RING finger and WD repeat domain 3 (RFWD3) that positively regulates p53 stability in response to DNA damage as a therapeutic target in cancers.
View Article and Find Full Text PDFArticle Synopsis
- Conventional liquid chromatography struggles to effectively separate both hydrophilic and lipophilic compounds in herbal medicines, posing a challenge for comprehensive analysis.* -
- A new method using a combination of reversed-phase and hydrophilic interaction liquid chromatography-tandem mass spectrometry allows for simultaneous analysis of 27 components in a herbal extract, including 9 hydrophilic and 18 lipophilic compounds.* -
- The technique demonstrated the ability to monitor up to 69.9% of the content in one injection within 15 minutes, significantly improving over previous methods and enhancing control over herbal medicine quality.*