Publications by authors named "Qin-Wei Ji"
Article Synopsis
- - The study investigates the role of CD4(+) latency-associated peptide (LAP)(+) regulatory T cells (Tregs) in patients with acute coronary syndrome (ACS), a condition not previously explored in this context.
- - In the research involving 111 ACS patients and 117 control patients, findings showed that ACS patients had significantly lower levels and functionality of CD4(+)LAP(+) Tregs, indicating potential immune system dysfunction.
- - The researchers concluded that this novel Treg subset is defective in ACS patients, as evidenced by reduced expression of GARP and lower levels of TGF-β in their blood, while IL-10 levels remained similar between the two groups.
Background: CXCL16 has been shown to be involved in atherosclerotic lesion development, but its role in preexisting lesions is still unclear. This study aims to assess the effect of CXCL16 on the stability of preexisting lesions.
Methods: We firstly measured plasma CXCL16 level in Apolipoprotein E-Knockout (ApoE KO) mice with either high-cholesterol diet (HCD) or normal diet (ND) by enzyme-linked immunosorbent assay (ELISA).