Publications by authors named "Qin-Fang Yuan"
Article Synopsis
- Cuprotosis is a new type of programmed cell death linked to cancer, and its role in gastric cancer (GC) is currently being explored.
- Researchers analyzed data from 1544 GC patients, identifying three distinct molecular genotypes: Cluster A (best outcomes, metabolic pathway enrichment), Cluster B (high immune activation), and Cluster C (immunosuppressed with poor immunotherapy response).
- The study also developed a scoring system for cuprotosis that can predict patient survival and immune responses, highlighting new potential targets for immunotherapy in GC patients.
Objective: The aim of the study was to propose a signature based on genes associated with antigen processing and presentation (APscore) to predict prognosis and response to immune checkpoint inhibitors (ICIs) in advanced gastric cancer (aGC).
Background: How antigen presentation-related genes affected the immunotherapy response and whether they could predict the clinical outcomes of the immune checkpoint inhibitor (ICI) in aGC remain largely unknown.
Methods: In this study, an aGC cohort (Kim cohort, RNAseq, N=45) treated by ICIs, and 467 aGC patients from seven cohorts were conducted to investigate the value of the APscore predicting the prognosis and response to ICIs.
Background: Patients with diabetic foot ulcer (DFU) usually have a poor quality of life (QoL) and self-efficacy, which is affected by many risk factors. However, the role of psychological resilience in QoL and self-efficacy in DFU patients has remained unclear.
Methods: This prospective cross-sectional study was performed in a single center from January 2018 to February 2020.
In February 2020, the exponential growth of COVID-19 cases in Wuhan city posed a huge economic burden to local medical systems. Consequently, Wuhan established Fangcang Shelter hospitals as a One Health approach for responding to and containing the COVID-19 outbreak by isolating and caring for mild-to-moderate cases. However, it is unclear to what degree the hospitals contained COVID-19.
View Article and Find Full Text PDFBackground: A novel coronavirus emerged in China in December 2019, and human-to-human transmission was previously identified. This study aimed to compare the epidemiological characteristics in Jiangsu Province and assess whether so-called wartime control measures changed the trend of coronavirus disease 2019 (COVID-19) in the province.
Methods: Epidemiological data were obtained from the websites of China's Bureau of Health and the People's Government of Jiangsu Province and informal online sources from January 22 to February 20, 2020.